Stability Analysis and Optimal Control of Vaccination and Treatment of a SIR Epidemiological Deterministic Model with Relapse

Abstract

In this paper, we studied and formulated the relapsed SIR model of a constant size<br /> population with standard incidence rate. Also, the optimal control problem with treatment<br /> and vaccination as controls, subject to the model is formulated. The analysis carried out<br /> on the model, clearly showed that the infection free steady state is globally asymptotically<br /> stable if the basic reproduction number is less than unity, and the endemic steady state,<br /> also, is globally asymptotically stable if the basic reproduction number (R0) is greater than<br /> unity. The results obtained from the simulations were analyzed and discussed.