Biosynthesis of copper oxide nanoparticles using leaves extract of Leucaena leucocephala L. and their promising upshot against diverse pathogens

Abstract

This contribution reports an ecological benevolent route for the fabrication of copper oxide nanoparticles (CuONPs) using Leucaena leucocephala L. leaves extracts at room temperature. Phytochemical screening of the fresh aqueous leaves extract showed the presence of tannins, saponins, coumarins, flavonoids, cardial glycosides, steroids, phenols, carbohydrates and amino acids. Copper oxide particles such prepared are in Nano scale and their morphology and size are characterized using field emission scanning electron microscopy, energy-dispersive X-ray spectroscopy, transmission electron microscopy, X-ray diffraction, Fourier transform Infra-red spectroscopy, Brunauer-Emmett-Teller, Barrett-Joyner-Halenda and Photoluminescence analysis. Furthermore, CuO-NPs evinced remarkable antimicrobial, antimalarial and antimycobacterial activity against diverse human pathogens.