Survey of antibiotic susceptibility pattern in microorganisms isolated from clinical samples in Shahid Faghihi hospital of Shiraz, Iran

Abstract

Antibiotic resistance is a public concern, worldwide. The purpose of this study was to survey the antibiotic susceptibility pattern in the microorganisms isolated from the clinical samples in Shahid Faghihi hospital of Shiraz, Iran. In this study, the microorganisms were isolated from the blood, bone marrow, pleural fluid, CSF and Vaginal discharge. Antibiotic susceptibility test was performed by the disk diffusion method according to Clinical and Laboratory Standards Institute (CLSI) standards. Out of 1344 samples, 306 (22.7%) various organisms were obtained. The highest and lowest isolates were related to blood (94.8%) and bone marrow (1.2%), respectively. Among all isolates, Staphylococcus aureus (32.6%) was the most common bacterium. Escherichia coli with 20.9% and Staphylococcus aureus with 64.9% were the most common Gram-negative and Gram-positive isolated bacteria, respectively. Antibiotic susctibility test results also showed that the highest and lowest resistances were related to Acinetobacter and Salmonella, respectively. Awareness of the antibiotic resistance can lead to proper administration of antibiotics in treating of bacterial infections and preventing antibiotic resistance.