The Relationship between Eating Disorders and ICAM-1, E-selection and Ghrelin Resting Level in Overweight People

Abstract

<em>Introduction</em> <br/>There is an agreement that eating disorder is related to psychological characteristics and on the other hand, level of ghrelin hormone, Intercellular adhesion molecule-1 (ICAM-1) and E-selection also change during eating disorders. We aimed to study the relationship between eating disorders and rest levels, ICAM-1, E-selection, and ghrelin hormone in obese people. <br/><em>Materials and Methods</em> <br/> In this quasi-experimental study, 120 obese men (25-30 years old) were purposefully selected. Then the data about their eating disorders gathered with eating attitudes test (EAT-26) questionnaire. In the next phase in the rest condition and after overnight fasting, blood samples are collected for measurement of rest levels, ICAM-1, E-selection, and ghrelin hormone. Finally the data were analyzed with appropriate statistical tests in SPSS version 18. <br/><em>Results</em> <br/>Mean and deviation of rest levels, ICAM-1, E-selection, and ghrelin hormone were respectively 3064.19, 61.5±19.7, and 2.5±1.5 and there was not any statistical significance relationship between eating disorders ICAM-1, E-selection, and ghrelin hormone in obese men (P<0.05(. <br/><em>Conclusion</em> <br/> According to our results, the prevalence of eating disorders can be a reason other than rest Levels, <br/>ICAM-1, E-selection, and ghrelin hormone.