A Modified Method for the Synthesis of Nitrofurazone

Abstract

Nitrofurazone is one of the antibacterial nitrofuran agents used topically for skin infections. The drug is effective on the majority of infectious microorganisms. Because of the importance of this drug in clinic, in this study various methods of synthesis of nitrofurazone were examined and the most appropriate method, applicable to pharmaceutical industry was chosen and optimized from the points of quality and yield.