مرور Volume 10, Issue 4 بر اساس تاریخ انتشار

در حال نمایش موارد 1 - 20 از 27

  • Selective COX-2 Inhibitors: A Review of Their Structure-Activity Relationships 

    Zarghi, Afshin؛ Arfaei, Sara (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    Non-steroidal anti-inflammatory drugs (NSAIDs) are the competitive inhibitors of cyclooxygenase (COX), the enzyme which mediates the bioconversion of arachidonic acid to inflammatory prostaglandins (PGs). Their use is ...

  • Metformin Treatment in Hyperglycemic Critically Ill Patients: Another Challenge on the Control of Adverse Outcomes 

    Panahi, Yunes؛ Mojtahedzadeh, Mojtaba؛ Zekeri, Nuria؛ Beiraghdar, Fatemeh؛ Khajavi, Mohammad-Reza؛ Ahmadi, Arezo (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    New-onset hyperglycemia in patients admitted to intensive care units increases the risk of morbidity and mortality. Insulin resistance is frequently seen in the treatment of stress-induced hyperglycemia. Metformin, an oral ...

  • Diuretic Potential of Whole Plant Extracts of Pergularia daemia (Forsk.) 

    Vyas, Bhavin؛ Ruchi, Vyas؛ DD, Santani (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    The whole plant, Pergularia daemia (Family: Asclepediaceae), was extracted with 50% alcohol and a fresh batch of the plant material was successively extracted with petroleum ether, ethyl acetate and n-butanol to determine ...

  • Synthesis and Antimycobacterial Activity of 2-(Phenylthio) benzoylarylhydrazone Derivatives 

    Almasirad, Ali؛ Samiee-Sadr, Somayeh؛ Shafiee, Abbas (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    A series of new 2-(phenylthio) benzoylaryl hydrazones were synthesized by acid-catalyzed condensation of hydrazide 3 with corresponding aldehydes. The chemical structures of the compounds were elucidated by FT-IR, 1H-NMR ...

  • The Significance Application of Indigenous Phytohemagglutinin (PHA) Mitogen on Metaphase and Cell Culture Procedure 

    Movafagh, Abolfazl؛ Heydary, Hassan؛ Mortazavi-Tabatabaei, Seyed AbdolReza؛ Azargashb, Eznollah (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    Phytohemagglutinin (PHA) is a lectin, obtained from the red kidney bean that binds to the membranes of T-cells and stimulates metabolic activity, cell division, etc. The object of this research was the comparison between ...

  • Pharmacological Action of Mentha piperita on Lipid Profile in Fructose-Fed Rats 

    Mani Badal, Rajendra؛ Badal, Divya؛ Badal, Pourush؛ Khare, Ashish؛ Shrivastava, Jyoti؛ Kumar, Vinod (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    Cardiovascular diseases with an incidence of approximately 50% are the main causes of death in most advanced countries and an increasing trend in the developing world as well. The World Health Organization estimates that ...

  • Involvement of Lysosomal Labilisation and Lysosomal/mitochondrial Cross-Talk in Diclofenac Induced Hepatotoxicity 

    Pourahmad, Jalal؛ Mortada, Yassar؛ Eskandari, Mohammad Reza؛ Shahraki, Jafar (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    In this research, we investigated the cytotoxic mechanisms of one of the widely used pharmaceuticals that are regularly associated with the adverse effects on the liver, sometimes leading to acute liver failure, diclofenac. ...

  • Use of Growing Cells of Pseudomonas aeruginosa for Synthesis of the Natural Vanillin via Conversion of Isoeugenol 

    Ashengroph, Morahem؛ Nahvi, Iraj؛ Zarkesh-Esfahani, sayyed Hamid؛ Momenbeik, Fariborz (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    The great demand of people for consumption of natural additives resulted in producing natural vanillin. There are plant sources and chemical procedures for vanillin production but microbial bioconversions are being sought ...

  • Larvicidal Activity of Centaurea bruguierana ssp. belangerana against Anopheles stephensi Larvae 

    Khanavi, Mahnaz؛ Rajabi, Afsaneh؛ Behzad, Masoud؛ Hadjiakhoondi, Abbas؛ Vatandoost, Hassan؛ Abaee, Mohammad Reza (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    In this study, the total 80% of MeOH extract and also petroleum ether, CHCl3, EtOAc, n-BuOH, and the remaining MeOH fractions obtained by solvent-solvent fractionation of the whole flowering samples of Centaurea bruguierana ...

  • Mycotoxins: Analytical Challenges 

    Yazdanpanah, Hassan (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    Mycotoxins are natural secondary fungal metabolites produced on agricultural commodities. Mould and mycotoxin contamination may occur before harvesting, between harvesting and drying, and during storage. FAO has estimated ...

  • A Validated HPTLC-Densitometric Method for Assay of Aucubin in Vitex agnus-castus L. 

    Hajimehdipoor, Homa؛ Shekarchi, Maryam؛ Pirali Hamedani, Morteza؛ Abedi, Zahra؛ Gohari, Ahmad Reza؛ Shekarchi, Maral (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    Vitex agnus-castus L. is a medicinal plant which is used in several dosage forms for women hormonal disorders and standardized according to the iridoids or flavonoids content. Aucubin, an iridoid glycoside, considered as ...

  • Antinociceptive and Anti-inflammatory Effects of Pistacia vera Leaf Extract in Mice 

    Hosseinzadeh, Hossein؛ Behravan, Effat؛ Soleimani, Mohammad M (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    Pistacia vera L., a member of Anacardiaceae family, has been used for sedation and analgesia in traditional medicine. In this study, the antinociceptive and anti-inflammatory effects as well as acute toxicity of the aqueous ...

  • Evaluation of Enamel Matrix Derivative (EMD) Teratogenicity on the Rat Embryo Neural Crest Culture 

    Mamashli, Maliheh؛ Ramezani, Mina؛ Parsa, maliheh؛ Ostad, Seyed Naser (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    Enamel matrix derivative Emdogain (EMD) is widely used in periodontal treatment in spite of the fact that its effect on the developing embryo has not been elucidated. The aim of this study was to investigate the teratogenic ...

  • Phytochemical Investigation of Vinca Minor Cultivated in Iran 

    Farahanikia, Behnaz؛ Akbarzadeh, Tahmineh؛ Jahangirzadeh, Akbar؛ Yassa, Narguess؛ Shams Ardekani, Mohammad Reza؛ Mirnezami, Tahmineh؛ Hadjiakhoondi, Abbas؛ Khanavi, Mahnaz (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    Lesser Periwinkle (Vinca minor L.), a member of Apocynaceae, is not only an ornamental plant with lilac-blue flowers, but also a medical plant producing an important alkaloid, vincamine, found in the leaves which shows a ...

  • Effects of Selective iNOS Inhibitor on Spatial Memory in Recovered and Non-Recovered Ketamine Induced Anesthesia 

    Tabrizian, Kaveh؛ Najafi, Sheyda؛ Belaran, Maryam؛ Hosseini-Sharifabad, Ali؛ Azami, Kian؛ Soodi, Maliheh؛ Kazemi, Ali؛ Kebriaeezadeh, Abbas؛ Sharifzadeh, Mohammad (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    Nitric oxide (NO) is thought to be involved in spatial learning and memory in several brain areas such as hippocampus. This study examined the effects of post-training intrahippocampal microinjections of 1400W as a selective ...

  • Determination of Methotrexate in Biological Fluids and a Parenteral Injection Using Terbium-Sensitized Method 

    Jouyban, Abolghasem؛ Shaghaghi, Masoomeh؛ L. Manzoori, Jamshid؛ soleymani, Jafar؛ Vaez-Gharamaleki, Jalil (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    A new sensitive, simple and rapid method for determination of methotrexate (MTX) was developed based on quenching effects of MTX on the fluorescence intensity of Tb3+-1,10-phenanthroline complex. The fluorescence intensity ...

  • Synthesis and Cytotoxic Evaluation of Some Novel Sulfonamide Derivatives Against a Few Human Cancer Cells 

    Mirian, Mina؛ Zarghi, Afshin؛ Sadeghi, Sedighe؛ Tabaraki, Parisa؛ Tavallaee, Mojdeh؛ Dadrass, Orkideh؛ Sadeghi-Aliabadi, Hojjat (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    Sulfonamides are the first effective chemotherapeutic agents used for several years to cure or prevent systemic bacterial infections. In addition, this agents showed anti-carbonic anhydrase and cause cell cycle perturbation ...

  • Synthesis, Spectral Characterization, In-vitro Antibacterial and Antifungal Activities of Novel (2e)-Ethyl-2-(2-(2, 4-Dinitrophenyl) Hydrazono)-4-(Naphthalen-2-yl)-6-Arylcyclohex-3-Enecarboxylates 

    Kanagarajan, V.؛ Thanusu, J.؛ Gopalakrishnan, M. (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    In a search for new leads towards potent antimicrobial agents, an array of novel (2E)-ethyl-2-(2-(2,4-dinitrophenyl)hydrazono)-4-(naphthalen-2-yl)-6-arylcyclohex-3-ene carboxylates 17-24 were synthesized and characterized ...

  • Physiochemical Characterization and Release Rate Studies of Solid Dispersions of Ketoconazole with Pluronic F127 and PVP K-30 

    Kumar, Pankaj؛ Mohan, Chander؛ Uma Shankar, Mara Kanam Srinivasan؛ Gulati, Monica (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    In the present study solid dispersions of the antifungal drug Ketoconazole were prepared with Pluronic F-127 and PVP K-30 with an intention to improve its dissolution properties. Investigations of the properties of the ...

  • Study of Drug-Drug Interactions in Prescriptions of General Practitioners and Specialists in Iran 2007-2009 

    Ahmadizar, Fariba؛ Soleymani, Fatemeh؛ Abdollahi, Mohammad (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2011-12-01)
    Prescriptions written by general practitioners and medical specialists were studied and compared to determine the type, time of onset and clinical importance of drug-drug interactions (DDIs) in an attempt to reduce further ...