Neutrophil-lymphocyte Ratio Findings and Larynx Carcinoma: a Preliminary Study in Turkey

Abstract

<b>Background:</b> To identify the potential prognostic role of the neutrophil/lymphocyte (N/L) ratio in larynxcarcinoma. Materials and <br/><b>Methods</b>: Oncologic archive charts of patients with a larynx carcinoma diagnosisbetween the years 2010 and 2013 were retrospectively reviewed. The inclusion criterion was to be availablewith hemogram test prior to diagnostic procedure. Patients undergoing septorinoplasty comprised the controlgroup. <br/><b>Results</b>: There were 65 cases in the study and 42 cases in control group meeting inclusion criteria. Ingeneral a non-significant increase in N/L ratio was observed with increasing tumor size and stage (p>0.05) inlarynx carcinoma. The N/L ratio was found to be significantly higher in larynx carcinoma compared to controlgroup (p=0.004). <br/><b>Conclusions</b>: In conclusion, the N/L ratio was shown to be significantly increased in larynxcarcinomas compared to control group. Further studies are needed to assess any prognostic role.