Results of Cervical Cone Excision Biopsy in Iran

Abstract

Aims: The prevalence of cervical cancer in a developing country, and diagnostic therapeutic value of knifeconization for CIN, indications, cytopathologic results and complications of conization, were evaluated. <br/><b>Methods</b>:This retrospective- descriptive study concerned 44 cases that underwent conization. <br/><b>Results</b>: The age range ofpatients was 18-75 (mean=43), and parity ranges were from 0-10 (mean 4-5), ten cases were post-menopausal.The main indication was inability to visualize the entire T zone (19 cases) that was more prevalent in postmenopausal(5 cases and 14 cases premenopausal). The most common pap smear result was HSIL in 16 casesbefore conization. The most common colposcopic biopsy result was moderate dysplasia in 16 cases. Two caseshad invasive cancer on colposcopic- biopsy: one of them had ASCUS in pap smear result and another oneHSIL. The most common histologic result after conization was mild dysplasia in 23 cases. Four cases had invasivecancer in histology of the cervix with conization. Active hemorrhage occurred in 2 cases and urinary infection in1 case after conization. <br/><b>Conclusions</b>: Pap smear results in screening of cervical cancer are not reliable andcolposcopy is more acceptable for LSIL and ASCUS. All gynecologist should develop the skill to perform accurateknife conization, because the classical indications for conization continue to be valid, and it has low risk ofcomplications.