Family History and Mortality in the Japan Collaborative Cohort Study for Evaluation of Cancer (JACC)

Abstract

To determine the influence of family medical history on mortality from cancer and other chronic diseases,participants in the JACC study were questioned about tuberculosis, apoplexy, hypertension, heart disease, diabetesmellitus and malignant diseases and followed up. Consistent across the sexes, a family history of tuberculosiswas apparently linked to reduced risk of lung cancer, and also lowered ischemic heart disease. No consistentfindings were obtained for hypertension, diabetes mellitus or cancer.