Multidrug resistance is a principal mechanism by which tumors become resistant to structurally andfunctionally unrelated anticancer drugs. Resistance to chemotherapy has been correlated with overexpression ofp-glycoprotein ...

The objective of this study was to determine the prevalence of significant lesions defined as high gradesquamous intraepithelial lesions (HSIL), adenocarcinoma in situ (AIS) and invasive carcinoma in women whohad HPV-positive ...

Background: Breast cancer is the most common cancer in women. One way to decrease the burden ofthis cancer is early detection through mammography. This study compared the effectiveness of two differenteducational ...

idence. Of all cancer types, cervical cancer is reported to be the fourth most common cancer in women, and theseventh overall, with an estimated 528,000 new cases worldwide in 2012. It features a long preclinical phase ...

Background: Chromosomal aberrations identified in acute lymphoblastic leukemia (ALL) have an importantrole in disease diagnosis, prognosis and management. Information on karyotype and associated clinical parametersare ...

Background: Mean platelet volume (MPV) is a marker which has been investigated in many cancers but datafor head and neck lesions are limited. We aimed to study the MPV levels in head and neck cancers as a diagnosticmarker. ...

Gastric cancer (GC) is the fifth most common cancer in the world, with a wide variation in incidence ratesacross different geographical areas. In Iran GC is the most common cancer in males and it is reported to bethe third ...

This study was conducted to determine whether advancing age is an independent predictor of increased risk ofhigh-grade pathologies among women referred for colposcopy after abnormal cervical cytology. Medical recordswere ...

Background: Oral cancer is a health problem in Thailand. Cratoxylum formosum subsp. pruniflorumGogel (Teawdang), normally consumed in northeast Thailand, has proven cytotoxic to cervical cancer celllines including ...

Omega-3 polyunsaturated fatty acids (w-3 PUFAs) are essential nutrients for human beings and theirpotential roles against cancer development and progression have become of wide concern recently. Some studieshave suggested ...

Glioblastoma, also known as glioblastoma multiforme (GBM), is the most aggressive of human braintumors and has a stunning progression with a mean survival of one year from the date of diagnosis. High cellproliferation, ...

Clinical evidence shows that dual inhibition of kinases as well angiogenesis provides ideal therapeutic optionin the treatment of medullary thyroid carcinoma (MTC) than inhibiting either of these with the events ...

Background: Awareness and attitudes of nurses regarding end of life care are important factors in providinghospice care. In an extensive literature review, we found no related articles investigating Iranian nurses ...

Background: Currently, a comprehensive program for screening and early detection of cervical cancer doesnot exist in Iran. This study aimed to determine the prevalence of abnormal Papanicolaou (Pap) smears andsome ...

Background: Ovarian cancer is the third most common cause of cancer in Indian women. Despite an initial70-80% response rate, most patients relapse within 1-2 years and develop chemoresistance. Hence, identificationor ...

Breast cancer, the most common cancer in the women, is the leading cause of death. Necrotic signalingpathways will enable targeted therapeutic agents to eliminate apoptosis-resistant cancer cells. In the presentstudy, the ...

Background: Oral carcinoma (OC) remains one of the most difficult malignancies to cure. Hesa-A is anIranian herbal-marine compound that has shown promising anti-tumor properties against various human tumors.However, ...

Background: Essential thrombocythemia (ET) is a clonal hemopoietic stem cell myeloproliferative neoplasmcharacterized by persistent thrombocytosis along with megakaryocytic hyperplasia. In the last decade followingthe ...

Background: Breast cancer accounted for almost 25% of all cancers in women globally in 2012. Althoughbreast cancer is the most prevalent cancer in India, there is no organised national breast cancer screeningprogramme. ...

Background: Although radiotherapy is one of the most effective strategies in the treatment of cancers, it isassociated with short and long term side effects on normal tissues. Zataria multiflora Boiss (Laminacea) ...