Volume 13, Issue 7
مرور بر اساس
ارسال های اخیر
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Experience of Southern Chinese: New Challenges in Treating Young Female Breast Cancer Patients at Child-bearing Age - a Call for Multi-disciplinary Collaboration
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Compared with western populations, Southern Chinese, especially those residing in Hong Kong, areexperiencing increasing breast cancer incidence and also a younger onset of breast cancer. Combating thisproblem and treating ...
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Combined Screening of Cervical Cancer, Breast Cancer and Reproductive Tract Infections in Rural China
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Objectives: To investigate the current prevalence and knowledge of cervical cancer, breast cancer andreproductive tract infections (RTIs) in rural Chinese women, and to explore the acceptance and feasibility ...
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CHEK2 1100delC Variant and Breast Cancer Risk in Caucasians: A Meta-analysis Based on 25 Studies with 29,154 Cases and 37,064 Controls
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Links between the CHEK2 1100delC heterozygote and breast cancer risk have been extensively explored.However, both positive and negative associations with this variant have been reported in individual studies. Fora detailed ...
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Diagnostic Value of Interleukin 21 and Carcinoembryonic Antigen Levels in Malignant Pleural Effusions
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)The aim of this study was to evaluate the diagnostic value of interleukin 21(IL-21) and carcinoembryonicantigen (CEA) in tuberculous pleural effusions (TPEs) and malignant pleural effusions (MPEs). Pleuraleffusion samples ...
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Anti-metastatic Effects on B16F10 Melanoma Cells of Extracts and Two Prenylated Xanthones Isolated from Maclura amboinensis Bl. Roots
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Inhibitory effects of Maclura amboinenesis Bl, one plant used traditionally for the treatment of cancers, onmetastatic potential of highly metastatic B16F10 melanoma cells were investigated in vitro. Cell proliferationwas ...
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Silencing of Lysyl Oxidase Gene Expression by RNA Interference Suppresses Metastasis of Breast Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Objective: The aim of this study was to investigate possible mechanisms of LOX gene effects on invasion andmetastasis of breast cancer cells by RNA interference. Methods: LOX-RNAi-LV was designed, ...
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Hypermethylation of Suppressor of Cytokine Signaling 1 in Hepatocellular Carcinoma Patients
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Hepatocellular carcinoma (HCC), the most common primary hepatic tumor, is highly prevalent in the Asia-Pacific region, including Thailand. Many genetic and epigenetic alterations in HCC have been elucidated. Theaim of this ...
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Influence of Alcohol Consumption on Oxidative Stress and Antioxidant Status in Cancer Patients - Case-control Study from Western Nepal
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Aim: The present study assess the effect of consumption of alcohol on oxidative stress and antioxidant statusin patients suffering from different types of cancer. Methods: This hospital based case control study ...
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Histone Deacetylase Inhibitor Trichostatin A Enhances Antitumor Effects of Docetaxel or Erlotinib in A549 Cell Line
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Background and Objective: Histone deacetylase (HDAC) inhibitors represent a promising class of potentialanticancer agents for treatment of human malignancies. In this study, we investigated the effect of ...
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Association Between Polymorphisms of Dihydrofolate Reductase and Gamma Glutamyl Hydrolase Genes and Toxicity of High Dose Methotrexate in Children with Acute Lymphoblastic Leukemia
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Methotrexate (MTX) is an important drug for the treatment of childhood acute lymphoblastic leukemia(ALL). However, related toxicity occurs in many organs which may cause interruption of treatment, morbidity,and mortality. ...
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Survival Rate and Prognostic Factors of Esophageal Cancer in East Azerbaijan Province, North-west of Iran
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Background: Esophageal cancer in Iran is the sixth most common cancer and is particularly important ineast Azerbaijan. The aim of this study was to calculate survival rates and define prognostic factors in ...
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Follow up of Atypical Squamous Cell Pap Smears in Iraqi Women
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Objectives: To report the prevalence of atypical squamous cells of undetermined significance and atypicalsquamous cells-cannot exclude high squamous intraepithelial lesions and to determine the possible association ...
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TERT rs2736098 Polymorphism and Cancer Risk: Results of a Meta-analysis
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Objective: Several studies have demonstrated associations between the TERT rs2736098 single nucleotidepolymorphisms (SNPs) and susceptibility to cancer development. However, there are conflicting results. ...
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Oxaliplatin Sensitizes OS Cells to TRAIL-induced Apoptosis Via Down-regulation of Mcl1
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Purpose: To investigate the killing effect on OS cells of a combination of oxaliplatin and TRAIL and relatedmolecular mechanisms. Methods: TRAIL and oxaliplatin were applied to OS732 cells singly or jointly ...
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GSTP1, ERCC1 and ERCC2 Polymorphisms, Expression and Clinical Outcome of Oxaliplatin-based Adjuvant Chemotherapy in Colorectal Cancer in Chinese Population
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Aim: Platinum agents have shown to be effective in the treatment of colorectal cancer. We assessed whethersingle nucleotide polymorphisms (SNPs) in GSTP1, ERCC1 Asn118Asn and ERCC2 Lys751Gln might predictthe overall survival ...
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Predictors of Breast Cancer Screening Uptake: A Pre Intervention Community Survey in Malaysia
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Introduction: Despite health education efforts to educate women on breast cancer and breast cancer screeningmodalities, the incidence of breast cancer and presentation at an advanced stage are still a problem ...
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Association of Functional Polymorphisms of the XRCC4 Gene with the Risk of Breast Cancer: A Meta-analysis
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Objective: X-ray cross-complementing group 4 (XRCC4) is a major repair gene for DNA double-strand breaks(DSB) in the non-homologous end-joining (NHEJ) pathway. Several potentially functional polymorphisms of ...
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The Clinicopathological Significance of Bmi-1 Expression in Pathogenesis and Progression of Gastric Carcinomas
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Background: Oncogenic Bmi-1 (B-lymphoma Moloney murine leukemia virus insertion region-1) belongs to the Polycomb- group (PcG) family of proteins and plays an important role in the regulation of proliferation, ...
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Rapid Detection of Ovarian Cancer from Immunized Serum Using a Quartz Crystal Microbalance Immunosensor
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Background: The objective of this study was to measure the antibody content of NuTu-19 ovarian cancercells in serum samples using a quartz crystal microbalance (QCM) immunosensor. Materials and Methods:NuTu-19 ...
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Lack of Association Between LIG4 Gene Polymorphisms and the Risk of Breast Cancer: A HuGE Review and Meta-analysis
(West Asia Organization for Cancer Prevention (WAOCP), 2012-07-01)Objective: Non-homologous end joining (NHEJ) is one of the pathways of repair of DNA double-strandbreaks. A number of genes involved in NHEJ have been implicated as breast cancer susceptibility genes such asLIG4. ...
