Volume 15, Issue 5
مرور بر اساس
ارسال های اخیر
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Has the Neutrophil/Lymphocyte Ratio a Predictive Role in Distinguishing Neoplastic Potential of Colonic Polyps?
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)
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Tobacco Cessation in India: How Can Oral Health Professionals Contribute?
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Tobacco use is described as the single most preventable cause of morbidity and mortality globally, with theWorld Bank predicting over 450 million tobacco-related deaths in the next fifty years. In India, the proportion ...
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Effects of Thermotherapy on Th1/Th2 Cells in Esophageal Cancer Patients Treated with Radiotherapy
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Background: To investigate the effects of double radiofrequency hyperthermia on Th1/Th2 cells in esophagealcancer patients treated with radiotherapy. Materials and Methods: 22 patients with esophageal ...
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Anthocyanins: Targeting of Signaling Networks in Cancer Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)It is becoming progressively more understandable that phytochemicals derived from edible plants haveshown potential in modelling their interactions with their target proteins. Rapidly accumulating in-vitroand in- vivo ...
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The NAD(P)H: Quinine Oxidoreductase 1 (NQO1) Gene 609 C>T Polymorphism is Associated with Gastric Cancer Risk: Evidence from a Case-control Study and a Meta-analysis
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)The association between the NAD(P)H:quinone oxidoreductase 1 (NQO1) gene C609T polymorphism(rs1800566) and gastric cancer has been widely evaluated, but a definitive answer is so far lacking. We firstconducted a case-control ...
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Efficacy and Safety of Selumetinib Compared with Current Therapies for Advanced Cancer: a Meta-analysis
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Background and Aim: Selumetinib is a promising and interesting targeted therapy agent as it may reverseradioiodine uptake in patients with radioiodine-refractory differentiated thyroid cancer. We conduct this metaanalysisto ...
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Importance of Volumetric Measurement Processes in Oncology Imaging Trials for Screening and Evaluation of Tumors as Per Response Evaluation Criteria in Solid Tumors
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Cancer, like any disease, is a pathologic biological process. Drugs are designed to interfere with the pathologicprocess and should therefore also be validated using a functional screening method directed at these ...
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GSTT1 is Deregulated in Left Colon Tumors
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Our aim was to determine GSTT1 expression levels in left colon tumors and paired normal tissue in orderto identify specific alterations in GSTT1 mRNA levels. Alterations in GSTT1 expression in twenty-four leftsidedcolon ...
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Influence of Ionizing Radiation on Ovarian Carcinoma SKOV-3 Xenografts in Nude Mice under Hypoxic Conditions
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Purpose: We aimed to detect the expression of HIF-1α, VEGF, HPSE-1 and CD31 in SKOV3 xenografts innude mice treated with different doses of ionizing radiation, trying to explore the possible mechanism of hypoxiaand ...
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Clinicopathologic and Diagnostic Significance of p53 Protein Expression in Papillary Thyroid Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Background: p53 protein expression has been detected immunohistochemically in papillary thyroidcarcinoma(PTC). We investigated the relations between its expression and clinicopathologic features and itssignificance ...
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Protein-protein Interaction Network Analyses for Elucidating the Roles of LOXL2-delta72 in Esophageal Squamous Cell Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Lysyl oxidase-like 2 (LOXL2), a member of the lysyl oxidase (LOX) family, is a copper-dependent enzyme thatcatalyzes oxidative deamination of lysine residues on protein substrates. LOXL2 was found to be overexpressedin ...
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Development of Polymeric Nanopaclitaxel and Comparison with Free Paclitaxel for Effects on Cell Proliferation of MCF-7 and B16F0 Carcinoma Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Paclitaxel is hydrophobic in nature and is recognized as a highly toxic anticancer drug, showing adverse effectsin normal body sites. In this study, we developed a polymeric nano drug carrier for safe delivery of the ...
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Lack of Effects of Dietary Folate Intake on Risk of Breast Cancer: An Updated Meta-analysis of Prospective Studies
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Background: Epidemiological findings are controversial relating to the relationship between dietary folateintake and the risk of breast cancer. We therefore conducted a meta-analysis of prospective cohort studies ...
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Curcumin Inhibits MHCC97H Liver Cancer Cells by Activating ROS/TLR-4/Caspase Signaling Pathway
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Curcumin can inhibit proliferation of liver cancer cells by inducing apoptosis, but the specific signalingpathways involved are not completely clear. Here, we report that curcumin inhibited proliferation of MHCC97Hliver ...
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Clinicopathologic Patterns of Adult Renal Tumors in Pakistan
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Background: Renal cancer is a serious public health problem which may be under reported and registeredin our setup, since the Karachi cancer registry documented only 43 cases out of 4,268 incident cancer cases over3 ...
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Meta Analysis of Treatment for Stage IE~IIE Extranodal Natural Killer /T Cell Lymphomas in China
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Objective: To evaluate early treatment for extranodal natural killer/T cell lymphoma (ENK/TCL) in Chinaand provide reference for clinical treatment of these patients. Methods: Computer-based retrieval ...
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Identification of a Novel Fusion Gene (HLA-E and HLA-B) by RNA-seq Analysis in Esophageal Squamous Cell Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Esophageal squamous cell carcinoma (ESCC) is the most common histologic subtype of esophageal cancerand is characterized by a poor prognosis. Determining gene changes in ESCCs should improve understandingof putative risk ...
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Ubiquitination of p53 is Involved in Troglitazone Induced Apoptosis in Cervical Cancer Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Peroxisome proliferator-activated receptor gamma (PPAR-γ), a ligand-dependent nuclear transcription factor,has been found to widely exist in tumor tissues and plays an important role in affecting tumor cell growth. Inthis ...
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In vitro Study of Nucleostemin as a Potential Therapeutic Target in Human Breast Carcinoma SKBR-3 Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Although nucleolar protein nucleostemin (NS) is essential for cell proliferation and early embryogenesisand expression has been observed in some types of human cancer and stem cells, the molecular mechanismsinvolved in ...
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Lack of Metformin Effects on Different Molecular Subtypes of Breast Cancer under Normoglycemic Conditions: An in vitro Study
(West Asia Organization for Cancer Prevention (WAOCP), 2014-05-01)Background: In the past few years, a considerable number of preclinical studies have been proposed metforminas a potential anticancer agent, but some of these studies suffer from a number of methodological limitationssuch ...
