Background: Epidemiological findings are controversial relating to the relationship between dietary folateintake and the risk of breast cancer. We therefore conducted a meta-analysis of prospective cohort studies ...

Objective: To investigate the effects of secondary left-sided portal hypertension (LSPH) on the radical operationrate of patients with pancreatic cancer and systemically evaluate the prognosis of patients with ...

In February 6-7th, the Thai National Cancer Institute, the International Agency for Research on Cancerand its Mumbai Hub for Cancer Registration, together with the International Association of Cancer Registriesand the ...

Although nucleolar protein nucleostemin (NS) is essential for cell proliferation and early embryogenesisand expression has been observed in some types of human cancer and stem cells, the molecular mechanismsinvolved in ...

Background: Single nucleotide polymorphisms (SNPs) affecting microRNA (miR) sequences may influencecarcinogenesis. Our current study primarily aimed to confirm previously conducted association studies betweenrs2910164 ...

Background: Tongue cancer is still a major health problem in most developing countries around the world.Statistics shown the number of tongue cancers, especially in early age, to be increasing, with poor ...

Background: Renal cancer is a serious public health problem which may be under reported and registeredin our setup, since the Karachi cancer registry documented only 43 cases out of 4,268 incident cancer cases over3 ...

Purpose: To evaluate the survival outcome of early stage endometrioid adenocarcinoma of the endometriumwith risk factors for locoregional recurrence treated with combined pelvic external beam radiotherapy (EBRT)and vaginal ...

Beclin 1 is a key factor for initiation and regulation of autophagy, which is a cellular catabolic processinvolved in tumorigenesis. To investigate the role of alternative splicing of Beclin1 in the regulation of autophagyin ...

The aim of the study was to investigate the results of bladder irrigation with Water for Injection (WFI)after transurethral resection of bladder tumours for comparison with those for adjuvant use of BCG. A total of239 ...

Background: The aim of this planned research was to determine the comfort and anxiety levels of women withbreast cancer receiving radiotherapy. Materials and Methods: This descriptive type study covered ...

The purpose of the present study was to evaluate the preventive effects of hydrazinocurcumin (HZC) ondiethylnitrosamine (DEN)-induced hepatocarcinogenesis in a male Sprague Dawley (SD) rat model. One hundredand twenty male ...

Background: It has been demonstrated that neutrophil:lymphocyte (NLR) and platelet:lymphocyte (PLR)ratios are associated with prognosis in cancer patients. The aim of this study was to investigate whetherpretreatment ...

Matrine, a main active component extracted from dry roots of Sophora flavecens , has been reported to exertantitumor effects on A549 human non-small lung cancer cells, but its mechanisms of action remain unclear. Todetermine ...

Chemotherapy has significantly improved the prognosis of cancer patients with various malignancies. However,female patients, especially those whoich are premenopausal, suffer from significant chemotherapy induced ovarianfunction ...

Background: Fluorouracil-based regimens have been widely accepted and recommended in the guidelinesfor treating patients with early or advanced staged colon cancer, although results are controversial. Here weperformed ...

4-Methylsulfinyl-3-butenyl isothiocyanate (MTBITC) found in the radish (Raphanus sativus L.), is a wellknownanticancer agent. In this study, the mechanisms of the MTBITC induction of cell apoptosis in humanA549 lung cancer ...

Lysyl oxidase-like 2 (LOXL2), a member of the lysyl oxidase (LOX) family, is a copper-dependent enzyme thatcatalyzes oxidative deamination of lysine residues on protein substrates. LOXL2 was found to be overexpressedin ...

Aims: To evaluate anti-cancer activity of Asparagus racemosus (AR) leaf extract on UOK146, a renal cellcarcinoma cell line, and explore its mechanism of action. Materials and Methods: Dried AR leaves were ...

Peroxisome proliferator-activated receptor gamma (PPAR-γ), a ligand-dependent nuclear transcription factor,has been found to widely exist in tumor tissues and plays an important role in affecting tumor cell growth. Inthis ...