Thai bitter gourd fruits (Momordica charantia Linn., TBG) has been previously demonstrated to possessphase II detoxificating enzymes inducing properties, as well as the ability to reduce phase I carcinogen activatingenzyme ...

Oligomeric proanthocyanidins (OPCs) are found mostly in red grape seeds. Many publications have reportedthat OPCs possess an excellent anti-oxidant effects. Since it could against cellular damage from reactive oxygenspecies ...

Background: Study of the mechanisms of apoptosis in tumor cells is an important field of tumor therapy andcancer molecular biology. Apoptosis triggered by activation of the mitochondrial-dependent caspase pathwayrepresents ...

The influence of the autophagy-related gene Beclin1 on proliferation, invasion and metastasis of the cervicalcancer CaSki cells and its possible mechanism in vitro were here targeted. After the overexpression vectorpcDNA ...

Cancer is a disease of gradual increase in incidence overall the world. Kurdistan Region in Iraq has beenexposed to several carcinogenic hazards. There are few reports about the increased risk of cancer in different citiesin ...

Background: With the development of technologies to look at the expression levels of hundreds of miRNAsat a time and the clear role of miRNAs in cancers, groups began looking at miRNAs profiles of different ...

Background: Genomic amplification of the human telomerase RNA gene (hTERC), located in thechromosome 3q26 region, has been documented in tumorigenesis. The present study was designed to detecthTERC amplification in ...

Dietary isothiocyanates (ITCs) found in cruciferous vegetables (Brassica spp.) has been reported to reducecancer risk by inducing phase II conjugating enzymes, in particular glutathione S-transferases (GSTs). Thiscase-control ...

Background and Ais: An epidemiological shift in the form of increase in the incidence of cancer and decreasein the incidence of smoking is universally realized today. This study was conducted to observe an association ...

Background: The incidence and mortality of esophageal cancer (EC) in some rural areas with poor healthresources in China are the highest around the world. In these areas, screening programs for EC are conducted ...

To determine the knowledge, attitudes and practices of Jamaican male medical consultants regarding prostatecancer screening in three departments within the University Hospital of the West Indies. The research design wasa ...

Introduction: The Pap smear test has been regarded as a promising cervical screening tool since 1940s. Yet itsimportance has been overlooked by beneficiaries in Malaysia. This underlines the need to identify ...

The impact of genomics and pharmacogenomics in the current arena of clinical oncology is well-established.In breast cancer, mutations in the BRCA1 and BRCA2 genes have been well-characterized to carry a high riskof the ...

Polymorphisms of glutathione S-transferase (GST) proteins are correlated with elevated risk of many cancersincluding hematologic malignancies. Particularly concerning acute promyelocytic leukemia (APL), the studies ...

Oral cancer is the most common cancer diagnosed in Indian men and is the leading cause of cancer deaths.Helicobacter pylori have been reported to be present in 0-40% of the cases with head neck cancer. A higherpercentage ...

This article reviews all related research and reports on nasopharyngeal cancer (NPC) histopathologicalclassifications worldwide. Despite continuous advance of Chinese and international NPC histopathologicalclassification ...

Introduction: Calcium has anti-proliferative and pro-differentiation effects on cells in vitro and can inhibitthe development of various cancers. While there is some epidemiologic evidence for an inverse relation ...

Objective: It is well established that treatment modalities against cancer have psychosocial and serious medicalside effects especially neurologic, learning, and intellectual disorders among children with cancer. ...

Background: Cancer, a major cause of morbidity and mortality in India can be prevented by early detectionthrough screening, for which, awareness is essential. Aim: Determining cancer awareness among low socioeconomicwomen ...

Purpose: Prostate cancer differs markedly in incidence across ethnic groups. Since this disease is influenced bycomplex genetics, it is many genetic factors may affect the level of susceptibility to development of the ...