The expression of superoxide dismutases (SODs) has been shown to differ between lung tumor and tumorfreetissues. In the present study, we investigated the association between serum SOD activity and the risk oflung cancer ...

In a search for novel circulating biomarkers for pancreatic cancer, we examined the association betweenserum soluble Fas (sFas) levels and superoxide dismutase (SOD) activity and the risk of death from pancreaticcancer in ...

Evidence suggests a link between adiponectin, an adipocytokine, and liver tumorigenesis. Different multimercomplexes of adiponectin, with low-molecular weight (LMW), middle-molecular weight (MMW) and highmolecularweight ...

Superoxide dismutases (SODs) are antioxidant enzymes that play a role in the defense system of the body.They may be involved in protection against carcinogenesis processes. In the present study, we investigate theassociation ...

Insulin-like growth factor (IGF)-I and IGF-II are important mitogen and IGF binding protein-3 (IGFBP-3)exerts opposite effects. However, the results of epidemiological studies on cancer influence are somewhatcontroversial, ...

The Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study) was planned in the late1980s as a large-scale cohort study of persons in various areas of Japan. In the present study, we conducted anested ...

Recent studies have linked elevated serum sFas levels to atherosclerotic disease among patients. Confirmingan association between obesity and serum sFas levels in healthy subjects would facilitate our understanding ofobesity ...

High levels of insulin-like growth factor (IGF)-I are reported to be associated with an increased risk ofprostate cancer. On the other hand, the insulin-like growth factor binding protein-3 (IGFBP-3) may decreasethe risk. ...

Biliary tract cancer, encompassing gallbladder and bile duct cancers, has a poor prognosis, but little is knownof the etiology. A nested case-control study was here conducted to evaluate the association between serum ...

Superoxide dismutase (SOD) is an antioxidant enzyme that acts to degrade superoxide, a major causitivefactor for oxidative stress associated with cancer, cardiovascular disease, and various other ailments. Here, toassess ...

The preventive effects of physical activity against cancer may partly be ascribable to a possible decrease ininsulin-like growth factor-I (IGF-I) induced by the activity. To examine the association of physical activity ...

Insulin-like growth factor (IGF)-I and its main binding protein, IGFBP-3, modulate cell growth and survival,and thus are thought to be important for tumor development. Carotenoids and retinol have been linked to theprevention ...

No observational study has examined whether cancer-related biomarkers are associated with diet in Japanese.We therefore assessed sex-specific food and nutrient intakes according to serum IGF-I, IGF-II, IGFBP-3, TGF-β1, ...

In this paper, we describe the methodology of the case and control selection for the first-wave nested casecontrolstudy within the JACC Study. Among the subjects participating in the cohort, serum samples of 42,249subjects ...