Conformational Study of some novel Methoxy Half-Analogues of Michler’s Ketone by NMR

Abstract

One series of half-analogues of Michler's ketone containing one or more terminal methoxy<br />substituents with variable tertiary amino groups have been used in this study. NMR spectral<br />results for the parent ketones confirm earlier findings that ortho proton shifts are apparently<br />independent from steric effects in derivatives of Michler's ketone because the ring current and<br />carbonyl-induced shifts are self-canceling.