Silica sulfuric acid: an efficient catalyst for the synthesis of substituted indazoles

Abstract

A simple extremely fast and efficient approach for the synthesis of substituted indazole in<br />good to excellent yield catalyzed by using silica sulfuric acid (SSA) in DMSO solvent at room<br />temperature. This is solid state reaction have been attracting the synthetic organic chemist as<br />they provided enhance reaction rates, less environmental pollution, greater selectivity, cleaner<br />products and manipulative simplicity. Various indazoles are obtained in moderate to excellent<br />yield.