Determination of ultra trace of thiosemicarbazide by adsorptive stripping voltammetric method

Abstract

In the present work, an adsorptive stripping voltammetric method using a hanging mercury<br />drop electrode (HMDE) was described in order to determine the ultra trace of thiosemicarbazide<br />in different real samples. The method is based on accumulation of thiosemicarbazide on mercury<br />electrode. The potential was scanned to the negative direction and the differential pulse stripping<br />voltammograms were recorded. The instrumental and chemical parameters were optimized. The<br />optimized conditions were obtained in pH of 10.0, accumulation potential of 0.00 mV,<br />accumulation time of 60 s, scan rate of 80 mV s-1 and pulse height of 50 mV. The relationship<br />between the peak current versus concentration was linear over the range of 0.50-100.00 ng mL-1.<br />The limits of detection were 0.03 ng mL-1 and the relative standard deviation at 5.00 and 50.00<br />ng mL-1 of thiosemicarbazide ion were obtained 2.1 and 1.7%, respectively (n = 8).