Antiplasmodial ativity of akaloids from Garcinia Parvifolia Miq. Stem Bark

Abstract

Garciniavalline (1), a novel aporphinoid alkaloid, in addition to four known alkaloids,<br />cleistopholine (2), O-methylmoschatoline (3), (-)-oliveroline (4) and (-)-oliveridine (5), were<br />isolated and characterized from Garcinia Parvifolia Miq. stem bark. Structural elucidation of<br />these compounds was established by spectroscopic methods. Among them, alkaloids (2) and (4)<br />exhibited antiplasmodial activity against Plasmodium falciparum