Salicylic Acid as a Bio-based and Natural Brønsted Acid Catalyst Promoted Green and Solvent-free Synthesis of Various Xanthene Derivatives

Abstract

In this research study, a green protocol for facile and eco-safe synthesis of 12-aryl-tetrahydrobenzo[<em>α</em>]xanthene-11-ones, 1,8-dioxo-octahydroxanthenes and 14-aryl-14<em>H</em>-dibenzo[<em>α,j</em>]xanthenes using salicylic acid as a bio-based and natural Brønsted acid catalyst in a one-pot, multi-component synthesis under solvent-free conditions is reported. The present methodology is an environmentally friendly approach for the synthesis of various xanthene derivatives. It also offers several merits including, good yields, short reaction times, efficient, eco-friendly, solvent-free conditions, and materials available