Complexation of Bis(acetylacetonate)oxovanadium(IV) with D–penicillamine at neutral medium

Abstract

Neutral bidentate N-O type complexe of VO(II) has been synthesized through condensation of Dpenicillamine,(<br />D-H2Pen), with Bis(acetylacetonate)- oxovanadium(IV),[VO(acac)2], at neutral<br />medium . The established schiff base(NO type) complex was characterized on the basis of IR and<br />mass spectroscopy techniques.Besides,D-H2Pen binding behavior to[VO(acac)2] has been studied<br />in thermodynamic viewpoint using Uv/Vis spectroscopy.The measurments were done in 5mM<br />phosphate buffer,pH 7.0 and various temperatures.The optical absorption spectra of<br />[VO(acac)2]were analyzed in order to obtain binding constants and stoichiometries using SQUAD<br />software.The results show that the best fitting corresponds to 1:2 metal to ligand, complex<br />between [VO(acac)2] and D-H2Pen.The estimation of binding constant at various temperatures<br />enabled us to calculate all of the thermodynamic parameters of binding using Van,t Hoff equation.