Effects of Nano Zinc Oxide on the Hind Limb Bud of NMRI mouse embryos

Abstract

Nanomaterials are particles with 10 to100 nanometer size. They can easily be transported<br />through the skin, lung alveoli, and placenta. Materials in nano scales show different properties<br />compared with the same materials in macro or larger scale. It is found that zinc element is an<br />essential metal for normal physiological functions. However increase or decrease of this element<br />during pregnancy, for example with using cosmetics and deodorants, can be teratogen and cause<br />several fetal abnormalities. Given this fact, this study was conducted to investigate the effects of<br />nano zinc oxide on the developmental stages of hind limb budsin NMRI mice embryos