Autism and autism spectrum disorders (ASDs) such as Rett syndrome and Asperger syndromeare enigmatic and complex neurodevelopmental disorders, thought to have originated inparticular interactions of genetic and ...

As a continuation of our efforts in developing new antimycobacterial agents, a series of new 1,3-thiazolidine-2-thione derivatives were synthesized. The chemical structures of the compounds were elucidated by FT-IR, 1H-NMR ...

Anethum graveolens L. (dill) is used widely in Asian food and folk medicine but its safety profile for further clinical studies has remained unclear. After administration of total hydroalcoholic extract to mice in acute, ...

Nanosilver has recently been recognized as an antimicrobial agent. Although this nanoparticlecan be used in medical applications but its dermal and systemic toxicity via dermal exposure hasnot been completely ...

Many biological effects of exposure to extremely low frequency electromagnetic fields(ELF-EMFs) have been documented, but little work carried out on plants. A meiotic study wasperformed on Brassica napus L as ...

Expression of recombinant proteins and drugs in Pichia pastoris has been in development since the late 1980s and the number of recombinant proteins produced in P. pastoris has increased significantly in the past several ...

A simple, fast, efficient and environmentally friendly method for synthesis of benzimidazole and its 2-alkyl, aryl and heteroaryl substituted derivatives was developed using zeolite HY. Two component cyclolcondensation of ...

Despite the critical role of erythropoietin (EPO) as therapeutic agent in treatment of anemia, its consumption is limited due to several disadvantages including the product short half-life, immunogenicity and susceptibility ...

Epilepsy is the oldest nervous system disorder known to mankind and one of the most common diseases in human population. Despite extensive studies, multiple aspects of the disease and the nature of the disorder are ...

Impaired glucose tolerance has several adverse effects on growing fetus. In this study we evaluated the effect of excessive weight gain during pregnancy on the risk of glucose intolerance in pregnant women. A case-control ...

A quantitative TaqMn Real-Time PCR assay was developed and its diagnostic value on human serum and livestock samples were evaluated. Brucella species could be distributed through communities as a biological agent. Rapid ...

The effects of chronic AlCl3 exposure on spatial memory in rats remain controversial. Since some toxic metals such as aluminum when entered the body, can contribute to diseases such as Alzheimer, in this study the time ...

A high-performance liquid chromatography with ultraviolet detection (HPLC/UV) methodwhich was used solid-phase extraction for cleanup, was developed for the determination ofAzinphos methyl ,Phosalone, Diazinon ...

A group of 1,3-biarylhydrazide derivatives possessing a COX-2 azido pharmacophore at the Para- position of the C-1 phenyl ring in conjunction with a N-3 phenyl or substituted-phenyl ring (4-F,4-Cl,4-OMe) were designed and ...

In modern clinical practice, combination fixed - dose tablets have become a baseline foreffective therapy in many clinical conditions. The Hydrochlorothiazide (Hctz) (12.5mg) /Lisinopril (Lis) (10 mg) tablet ...

One of the goals of medicinal chemistry research and drug discovery is to provide a rationalbasis for the design of new medicinal agents. Organic compounds and their reactions have beenutilized by people since ...

As majority of people around the world rely on non-conventional medicine mainly of herbalsources for their primary healthcare nowadays, the quality of herbal medicine is one of themost important issues. The ...

There are many different bacterial infections in the world that patients are suffering from and research teams are trying to find suitable ways to prevent and treat them. Urinary Tract Infections (UTIs) are most important ...

A simple extractive spectrophotometric method has been developed for the estimation of miconazole nitratein both pure and pharmaceutical preparation. The method is based on the formation of ion-pair complex of the

N,N-Diethyl meta Toluamide (DEET) is an insect repellent agent that contrary to its benefits,if is used in formulations with high skin permeation, will produce side effects of differentseverity. This study ...