Magnetic Nano Cobalt Ferrite: An efficient recoverable catalyst for synthesis of 2,4,5-trisubstituted imidazoles

Abstract

An efficient three-component synthesis of 2,4,5-trisubstituted imidazolesis described by one-pot condensation of aldehydes, diketones and ammonium acetate using CoFe₂O₄magnetic nanoparticles as an efficient and environmentally benign catalyst.The easy recovery of the catalyst and reusability, broad substrate scopes, high yields of products and ethanol as solvent make this protocol practical, environmentally friendly and economically attractive.