Analysis of fatty acid composition of Withania coagulans fruits by gas chromatography/mass spectrometry

Abstract

<strong>Background and objectives: </strong><em>Withania coagulans </em>Dunal (Solanaceae) fruits are recommended to treat asthma, dyspepsia, biliousness, flatulent colic, liver complaints, intestinal infections, strangury, wounds and as diuretic, emetic and sedative agent in Indian traditional system of medicine. The objective of this study was to describe the systematic fatty acid composition of the petroleum ether extract of <em>W</em>. <em>coagulans </em>fruits. <strong>Methods:</strong> Petroleum ether extract of <em>W</em>. <em>coagulans </em>fruits was prepared by maceration. Components of the <em>W</em>. <em>coagulans </em>petroleum ether extract were identified by gas chromatography-mass spectrometry and their concentrations were determined. <strong>Results:</strong> The fixed oil of <em>W. coagulans</em> fruits constituted of twenty nine components including unsaturated (52.36%) and saturated (22.15%) fatty acids, alkenes (5.65%), phytosterols (4.39%), fatty alcohols (4.14%), aromatic acid (3.56%), monoterpenes (3.22%), triterpenoids (1.83%) and alkanes (2.7%). Most of the saturated and unsaturated fatty acids were identified as their methyl esters. <strong>Conclusions: </strong>Palmitoleic and 11-eicosenoic acids have been reported for the first time in petroleum ether extract of the <em>W</em>. <em>coagulans </em>fruits. The present study has illustrated the chemical nature of <em>W. coagulans </em>fruit and described its fatty acids composition.