Nano-TiCl4.SiO2 Promoted One-Pot Synthesis of Amides or Nitriles from Aldehydes

Abstract

This research proposes an efficient and easy procedure for the preparation of amides or nitriles from aldehydes. Such materials were prepared via one-pot three component condensation reaction of various aldehydes in the presence of nano-TiCl4.SiO2 as a catalyst under thermal conditions. All reactions proceeded in high yields and in a moderately short reaction time. Meanwhile, oximes were obtained from aldehyeds in the presence of nano-TiCl4.SiO2.