Systematic review on toxicity outcomes of graphene oxide coated materials

Abstract

Graphene and its derived forms have surfaced as promising substances for a wide range of technological and biomedical purposes. However, it is crucial to evaluate their safety and potential risks to ensure their safe use. This systematic review examines the present state of knowledge regarding the toxicity of graphene oxide (GO) through in-vivo, in-vitro, and other species studies. The aim of this present research was to study toxicity outcomes of GO-coated materials. The literature search was conducted and most important electronic databases (20 studies) were checked and selected for the present study. The findings underscore the need for cautious consideration of GO's potential risks, especially at high concentrations and prolonged exposures. Continued research efforts are essential to gain a deeper understanding of the underlying mechanisms and to develop appropriate safety guidelines for the utilization of GO in various applications.