Evaluation of the Oncologic Outcomes of Breast Cancer According to the Smooth Implants Versus Textured Implants: A Systematic Review and Meta-analysis

Abstract

Background and aim: Concerns about the potential carcinogenic effects of breast implants, particularly those with textured surfaces, have recently been raised by an increasing number of reports of anaplastic large cell lymphoma associated with breast implants. The present study was conducted to evaluate oncologic outcomes of breast cancer according to the smooth implants vs. textured implants.Material and methods: For this systematic review and meta-analysis study, international databases such as MEDLINE (PubMed and Ovid), Web of Science, and Scopus were searched until July 2024 using keywords relevant to the study objectives. Cohort studies published in English that investigated the oncologic outcomes of breast cancer according to the surface type of implants were included in the study. STATA/MP. v17 software was used to analyze data.Results: Six studies were reviewed. The use of a textured implant vs smooth implant was associated with a significantly lower DFS (HR, 2.88; 95% CI, 1.71-4.04) vs (HR, 2.96; 95% CI, 1.57-4.35), (p<0.01).Conclusions: According to the results of the present meta-analysis, breast cancer recurrence may be related to the type of surface implant used for reconstruction.