Volume 3, Issue 1
مرور بر اساس
ارسال های اخیر
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Isolation, purification and identification of E. coli O157 phage for medical purposes
(Shiraz University of Medical Sciences, 2017-03-01)Phages are the most important natural antimicrobial agents. They have some important advantages in comparison with other chemical antibiotics. Escherichia coli (E. coli) as a Gram-negative bacteria belongs to the ...
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A reversed-phase high performance liquid chromatography approach for analysis of 5-Fluorouracil
(Shiraz University of Medical Sciences, 2017-03-01)A reproducible, sensitive, accurate and selective high performance liquid chromatographic (HPLC) method with ultraviolet absorbance detection has been developed and validated to quantitate 5-Fluorouracil (5-FU), an ...
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Drug utilization evaluation of meropenem: an important broad-spectrum antibiotic for the treatment of serious bacterial infections in hospitalized patients
(Shiraz University of Medical Sciences, 2017-03-01)Increasing trend in the development of antibiotic resistance is one the major concerns of health care systems throughout the world. Several factors are responsible of the emergence of this problem of which frequent ...
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Inhibition of CYP1A1 by pharmaceutical drugs, omeprazol and ketoconazole as a mechanism for activation of aryl hydrocarbon receptor (AHR)
(Shiraz University of Medical Sciences, 2017-03-01)Omeprazole (OMP) and ketoconazole (KTZ) have been shown to activate the AHR signaling pathway in spite of the fact that they bind to the receptor with low or no affinity. The aim of this study was to investigate whether ...
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Comparison of docking procedures and its efficiency for Betasecretase, Aromatase and Pyruvate dehydrogenase kinase inhibitors
(Shiraz University of Medical Sciences, 2017-03-01)Proper docking protocols were presented for three known enzyme structures, human betasecretase (BACE1), Aromatase and pyruvate dehydogenase kinase (PDHK) using Autodock4.2 and Vina softwares. The validity of docking protocols ...
