Volume 26, Issue 12
مرور بر اساس
ارسال های اخیر
-
Synergic effects of <i>Trigonella foenum-graecum</i>, <i>Ribes rubrum</i>, <i>Lavandula angustifolia</i>, and <i>Arctium Lappa</i> extracts mixture on learning and memory deficits in streptozocin-induced diabetic rats
(Mashhad University of Medical Sciences, 2023-12-01)Objective(s): The present study aimed to assess the efficacy of some known extracts on learning and memory impairment induced by streptozocin (STZ) in male rats.Materials and Methods: Eighty male rats were randomly divided: ...
-
Silicon nanoparticles: A promising approach for control of <i>Pseudomonas aeruginosa</i> biofilms
(Mashhad University of Medical Sciences, 2023-12-01)Objective(s): The current study aimed to investigate the control and treatment of biofilm-producing isolates of Pseudomonas aeruginosa using silicon nanoparticles (SiNPs). Materials and Methods: Biofilm-producing isolates ...
-
Expression of Galectin-9-related immune checkpoint receptors in B-cell acute lymphoblastic leukemia
(Mashhad University of Medical Sciences, 2023-12-01)Objective(s): Exhausted CD8+ T-cells over-express immune checkpoint receptors (ICRs), which interact with their ligands on malignant cells. However, some ICRs have been reported to be expressed on both T-cells and tumor ...
-
MiR181-5p promotes pathogenic angiogenesis of hepatopulmonary syndrome by negatively regulating Wnt inhibitor WIF1
(Mashhad University of Medical Sciences, 2023-12-01)Objective(s): Hepatopulmonary syndrome is a serious respiratory injury caused by chronic liver disease. Excessive pulmonary capillary angiogenesis is the key pathological event. However, the mechanism of microRNA regulatory ...
-
Crocin’s effect on phenotype switching of J774A.1 macrophages depends on their polarization state during exposure
(Mashhad University of Medical Sciences, 2023-12-01)Objective(s): Macrophages exhibit versatile phenotypes, with M1 macrophages releasing inflammatory cytokines and possessing microbicidal activities, while M2 macrophages release anti-inflammatory cytokines and contribute ...
-
Considering the protective effect of exendin-4 against oxidative stress in spiral ganglion neurons
(Mashhad University of Medical Sciences, 2023-12-01)Objective(s): The protection of spiral ganglion neurons (SGNs) is crucial for hearing loss. Exendin-4 has been shown to have neuroprotective effects in several neurological disorders. Therefore, this study aimed to investigate ...
-
Characteristics of <i>Streptococcus agalactiae</i> causing urinary tract infections: Emergence of new sequence types ST74 and ST38 in Iran
(Mashhad University of Medical Sciences, 2023-12-01)Objective(s): Difficult-to-treat Streptococcus agalactiae infections are increasingly described in patients with urinary tract infections (UTIs). This occurrence could be due to the production of virulence determinants. ...
-
Hepatoprotective effects of Gentisic acid through its anti-oxidant properties in nicotinamide-streptozotocin induced diabetic mice
(Mashhad University of Medical Sciences, 2023-12-01)Objective(s): Type 2 diabetes mellitus (T2DM) is a common metabolic disorder that causes many complications. Liver failure is one of the complications of T2DM. Oxidative stress plays a major role in the development and ...
-
Effect of a combined program of running exercise and environmental enrichment on memory function and neurogenesis markers in amyloid-beta-induced Alzheimer-like model
(Mashhad University of Medical Sciences, 2023-12-01)Objective(s): It is urgent to develop non-pharmacological interventions or multifactor combination approaches to combat Alzheimer's disease (AD). The effect of exercise (EX) combined with environmental enrichment (EE) on ...
-
Short-hairpin RNA-mediated suppression of cortactin may inhibit the migration and invasion abilities of endometrial cancer cells by reducing lamellipodia
(Mashhad University of Medical Sciences, 2023-12-01)Objective(s): The prognosis of endometrial cancer (EC) is significantly affected by tumor infiltration and metastasis. Cortactin (CTTN) regulates infiltration and metastasis in other tumors. Studies on the role and mechanism ...
-
Insights into the radiotherapy-induced deferentially expressed RNAs in colorectal cancer management
(Mashhad University of Medical Sciences, 2023-12-01)Radiotherapy (RT) has been commonly applied to treat advanced local cancers. In radiation therapy, high doses of radiation are utilized to trigger cell death. Radiation often leads to DNA double-strand breakages (DSB), ...
