BREAST CANCER MOLECULAR SUBTYPE CORRELATION WITH SONOGRAPHY

Abstract

Breast sonogram indication goes far not only for differentiation cystic or solid mass advanced solography of breast have ability to diagnosis malignant breast mass with high predictive value more than 95 %. The multiple features of malignant masses such as speculation, angular margin, posterior acoustic shadow, branching, vascularity and shape could help us to diagnosis luminal A, luminal B, her2 and triple negative, the calcification help us to know out come of diseases and prognosis as well to choose better managing of treatment, the 36 patient with proved breast cancer biopsy and subtype molecular calcification correlated with breast mass malignant features in sonogram and find out, luminal A have angular border and echogenic halo, luminal B have angular shape with posterior shadow and hyper vascular pattern on doppler images HER2 have angular margin and posterior enhancement and triple negative have oval shape and microloublation with at least 85% accuracy. how ever this calcification based on estrogen, progesterone and her 2 (epidermal growth factor) receptors, which have significant role on prognosis and endocrine therapy, chemotherapy, and type of surgery.