Volume 11, Issue 4
مرور بر اساس
ارسال های اخیر
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Acute Renal Failure: A Rare Initial Presentation of Acute Lymphoblastic Leukemia
(Shiraz University of Medical Sciences, 2020-10-01)Acute lymphoblastic leukemia has several presentations associated with bone marrow and extramedullary involvement. The unusual presentation may be due to the infiltration of leukemic cells in any organ. An 11-year-old girl ...
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Colon Cancer with Metastasis to the Right Atrium: A Case Report and Review of Literature
(Shiraz University of Medical Sciences, 2020-10-01)We report a case of colon cancer with pancreatic and interesting heart metastasis several months prior to disseminated metastases. The case was a 59-year-old man with a cecal cancer (T4N2); he received chemotherapy with ...
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New Variants in the CDH1 Gene in Iranian Families with Hereditary Diffuse Gastric Cancer
(Shiraz University of Medical Sciences, 2020-10-01)Background: Hereditary diffuse gastric cancer (HDGC) is a hereditable form of diffuse gastric cancer with very aggressive tumors, poor prognosis, and delayed clinical signs. Method: We ...
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Novel Protocol for Rapid Desensitization of Melphalan in a 5-Year-Old Boy Undergoing Conditioning for Hematopoietic Stem Cell Transplantation: A Case Report
(Shiraz University of Medical Sciences, 2020-10-01)Hematopoietic stem cell transplantation is a potentially life-saving therapy under certain conditions. Hypersensitivity reaction to chemotherapeutic drugs may interfere with this treatment. Griscelli syndrome type 2 is a ...
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SS18-SSX Rearrangement in Synovial Sarcoma Using Fluorescent in Situ Hybridization: A Report from an Iranian Population and Literature Review
(Shiraz University of Medical Sciences, 2020-10-01)Background: Synovial sarcoma is an aggressive soft tissue sarcoma. It has a wide spectrum of histopathologic patterns and uncertain immunohistochemistry, rendering it a diagnostic challenge. The objective ...
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Antiproliferative, Apoptotic, and Antimigration Property of Ethyl Acetate Extract of Calocybe indica against HeLa and CaSki Cell Lines of Cervical Cancer, and its Antioxidant and Mycochemistry Analysis
(Shiraz University of Medical Sciences, 2020-10-01)Background: The incidence rate of cervical cancer is increasing and its existing drugs are becoming more and more resistant. Therefore, we extracted the fruiting body of Calocybe indica edible mushroom in ...
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A Novel Combination of Pterostilbene and Dexamethasone Enhances Anti-proliferation and Apoptosis Induction Properties in Lymphoblastic Leukemia Cell Line
(Shiraz University of Medical Sciences, 2020-10-01)Background: T-cell acute lymphoblastic leukemia is an aggressive hematologic malignancy that results from the transformation of T-cell progenitors. Despite the significant advances in the current treatments, ...
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The Relationship of XPA and XPC Gene Polymorphisms with the Risk of Colorectal Cancer in Iran
(Shiraz University of Medical Sciences, 2020-10-01)Background: The objective of this study was to investigate the effect of several XPA and XPC polymorphisms on the risk of colorectal cancer (CRC) in northeastern Iran. Method: 180 CRC ...
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Prognostic Value of Aquaporin-3, Vimentin and E-cadherin Expressions in Invasive Breast Carcinoma: An Immunohistochemical Study
(Shiraz University of Medical Sciences, 2020-10-01)Background: The preponderance of breast cancer-related deaths are the result of local invasion and distant metastasis; therefore, it is necessary to identify the factors underlying invasion and metastasis ...
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The Utility of Serum HE4 in Predicting Myometrial Invasion in Patients with Endometrial Cancer
(Shiraz University of Medical Sciences, 2020-10-01)Background: Human epididymis protein 4 (HE4) is a novel tumor marker that has shown a strong potential in diagnosing and predicting the prognosis of endometrial cancer. In this study, we aimed to assess ...
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BRCA1/2 Expression Patterns in Different Grades of Oral Squamous Cell Carcinoma
(Shiraz University of Medical Sciences, 2020-10-01)Background: Oral squamous cell carcinoma (OSCC) is the sixth most common cancer worldwide and has a poor prognosis. The breast cancer 1 (BRCA1) and breast cancer 2 (BRCA2) genes are the key tumor suppressor ...
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In Silico Approach for Prediction of the Structural and Functional Impacts of 184(T>C) Missense Mutation Identified in BRCA1 Gene in a Syrian Breast Cancer Patient
(Shiraz University of Medical Sciences, 2020-10-01)Background: The classification of genetic variations depending on their clinical impacts is highly relevant for clinical decision-making. Therefore, predicting the effects of missense mutations using in ...
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Computational and Experimental Tools of miRNAs in Cancer
(Shiraz University of Medical Sciences, 2020-10-01)MicroRNAs (miRNAs) are short non-protein coding and single-stranded small RNA molecules with a critical role in the regulation of gene expression. These molecules are crucial regulatory elements in diverse biological ...
