Investigating Diverse Structure of Pulmonary Blood Vessels in Patients with Combined Pulmonary Atresia and Ventricular Septal Defect and Examining the Effect on Surgery Result

Abstract

<strong><em><span>Background</span></em></strong><br /> <span>This study aimed to investigate diverse structure of pulmonary blood vessels in patients with combined pulmonary atresia and ventricular septal defect and examine the effect on surgery result.</span><br /> <strong><em><span>Materials and Methods</span></em></strong><br /> <span>This cohort retrospective study was conducted on admittances to Tehran and Sari Hospitals at 2005-2016 for pulmonary atresia with ventricular septal defect (PA-VSD) with pulmonary artery (PA) anatomical variation. Diagnosis of pulmonary blood vessels in patients with PA-VSD was based on the results of CT Angiography (CTA), MRI, or cardioangiography examinations. Patients were followed up clinically by means of imaging in the course of initial repair, pre-definitive surgery preparation, and post-operative stages. All data sets were analyzed using Stata software version 13.0.</span><br /> <strong><em><span>Results</span></em></strong><br /> <span>Abundancy of PA-VSD classes A, B, and C was 34 (37.8%), 51 (56.7%), and 5 (5.6%) individuals respectively, while mean age and standard deviation of subjects for each of the said groups was 166.5±75.6, 135.79±5.3, and 108.4±152 months respectively. 38 (42.2%) were 1-year or younger at the time of initial surgery. As regards between-class age distribution, 18 (52.9%) individuals in group A, 20 (39.2%) individuals in group B, and the entire 5 individuals in group C were collectively above the age of 1 years old. </span><br /> <strong><em><span>Conclusion</span></em></strong><br /> <span>In view of the recent studies and the present investigation involving 90 patients with PA-VSD, it is easy to apprehend the large-scale applicability of complete-repair surgical interventions for patients suffering from this disease. This holds true specifically for class A patients who enjoy a longer lifespan and a more favorable prognosis. </span>