• Evaluation of β-actin as a Reference Gene for Comparative Expression Analysis of Equine Adipose- and Bone Marrow-Derived Mesenchymal Stem Cells by qRT-PCR 

  Nazari, Fatemeh؛ Parham, Abbas؛ Fani Maleki, Adham (Mashhad University of Medical Sciences, 2014-05-01)

  Background Bone marrow and adipose tissue are two main sources of mesenchymal stem cells (MSCs). Some of studies suggest that there are some differences in gene expression profile of MSCs-derived from various tissues. To ...

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• Effect of Purification of Human Adipose-derived Mesenchymal Stem Cells on the Expression of vWF Cell Factor Under Chemical and Mechanical Conditions 

  Gholami, N؛ Amoabediny, GH؛ Haghighipour, N؛ Amirzadeh, N؛ Mohammadnejad, J؛ Hasanzadeh, E (Mashhad University of Medical Sciences, 2014-05-01)

  Introduction: Human adipose-derived mesenchymal stem cells (hADSCs) are easily accessible in the body, and under appropriate conditions, they can be directed toward various phenotypes. Therefore, hADSCs have been considered ...

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• Comparative Analysis of Expression of Chemokoine Receptors CXCR4, CXCR6, CCR1 and CX3CR in Human Adipose-Drived Mesenchymal Stem Cell with Valproic Acid 

  Hasanzadeh-Moghadam, Maryam؛ Edalatmanesh Mohamad, Amin؛ Haddad Mashhadrizeh, Ali Akbar (Mashhad University of Medical Sciences, 2014-05-01)

  Introduction: Chemokine receptors are found on the surface of stem cells. There have been 19 distinct chemokine receptors described in mammals. Chemokines are major players in migration and homing. Therefore, changes in ...

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• Toxicity Study of Gelatin-chitosan Films with Bone Marrow Stromalcells Cultured in Rat 

  Karami Juyani, Afsane؛ Saberi, Mehdi؛ Kaka, Gholamreza؛ Jafari, Mahvash؛ Riyahi, Simin؛ Taghizadeh, Maliheh (Mashhad University of Medical Sciences, 2014-05-01)

  Background Gelatin and chitosan are known as biodegradable and biocompatible biopolymers.These biopolymers have recently receivedincreasingly more attention for tissueengineering.The aim of this ...

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• Evaluation of Crystal, Crack and Ethanol on viability of Mesenchymal Stem cells 

  Havakhah, Shahrzad؛ Hosseini, Azar؛ Hassan Zadeh3, Malihe (Mashhad University of Medical Sciences, 2014-05-01)

  Introduction Nowadays, due to drug abuse the world community has suffered  considerable  losses,  resulting  from productivity loss;  transmission  of  infectious  diseases; physical,  mental,  social  and  family  problems  ...

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• Stem Cells Application in Modeling of Human Genetic Diseases 

  Mollaei, Hoda؛ Khalaj-kondori, Mohammad (Mashhad University of Medical Sciences, 2014-05-01)

  The use of animal models in modeling of human genetic disease has many advantages. In some cases, however, this method may not be applicable due to some limitations, such as differences in tissue composition, anatomy and ...

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• Histological Evidences after Platelet-Rich-Plasma and Adipose Drived Stem Cells Injection on Critical Size Cleft Palate 

  Tavakolinejad, Sima؛ Hamidi Alamdari, Daryoush؛ Khajehahmadi, Saeedeh؛ Ebrahimzadeh Bidskan, Alireza (Mashhad University of Medical Sciences, 2014-05-01)

  Background Cleft palate (CP) is a common congenital defect. It makes serious difficulties for cleft-affected children. The gold standard of care is autogenous bone grafting which may cause additional problems in donor ...

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• Evaluation of Therapeutic Effects of Autologous Bone Marrow Mesenchymal Stem Cells to Prevent the Progression of Chronic Nephropathy in Renal Transplant 

  Ghasemi, Ali؛ Mamdouh, Freshteh؛ Gholami, Farhad (Mashhad University of Medical Sciences, 2014-05-01)

  Background Chronic allograft nephropathy(CAN)  is one of the most common causes of chronic and end stage renal disease. It  is defined with Mainly tubular atrophy and  interstitial fibrosis and no evidence of any other ...

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• The Current Status of Bone Marrow Transplantation in Treatment of Patients with Hemophilia 

  Mansouritorghabeh, Hassan؛ Modarresi, Alireza (Mashhad University of Medical Sciences, 2014-05-01)

  Background Bone marrow transplantation (BMT)is nowadays used in various hematological disorders including leukemias. Hemophilia A & B are sex linked bleeding disorders in which there are various genetic abnormalities in ...

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• Facts about Stem Cells and Importance of Them 

  Saeidi, Masumeh؛ Khakshour, Ali؛ Taghizadeh Moghadam, Habibolah؛ Faroughi, Foad؛ Rahban, Majid (Mashhad University of Medical Sciences, 2014-05-01)

  Stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide (through mitosis) to produce more stem cells. They are found in multicellular organisms. In mammals, there are ...

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• Reconstructionof Human Mandibular Continuity Defects with Allogenic Scaffold and Autologousmarrow Mesenchymal Stem Cells 

  Gholami, Mahdi (Mashhad University of Medical Sciences, 2014-05-01)

  Background Mandibular continuity defects occur after tumor resection, maxillofacial injury, or osteomyelitis. Despite the current availability of a plethora of treatment modalities, bone substitutes, and various clinical ...

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• Buccal fat pad: A location for obtaining adipose divide stem cells 

  Rahpeyma, Amin (Mashhad University of Medical Sciences, 2014-05-01)

  Background  Buccal fat pad is known as anatomic structure in between the masticatory muscles that separate these muscles from each other and surrounding bone. Ease of access, through the intraoral route makes it suitable ...

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• Potential use of Dental Pulp Stem Cell in Laboratory Studies and Clinical Trials 

  Tayarani-Najaran, Zahra؛ Pourgonabadi, Solmaz (Mashhad University of Medical Sciences, 2014-05-01)

  Stem cell-based therapy has great potential in treating health conditions including cardiovascular, autoimmune, type I diabetes, neurodegenerative and bone and cartilage diseases also in spinal cord injuries, malformations ...

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• The Role of Stem Cell Therapy in Multiple Sclerosis: an Overview of the Current Status of the Clinical Studies 

  Meamar, Rokhsareh؛ Dehghani, Leila؛ Nematollahi, Shahrzad؛ Tanhaee, Amirpoya (Mashhad University of Medical Sciences, 2014-05-01)

  The complexity of multiple sclerosis (MS) and the incompetence of a large number of promise treatments in MS urge us to plan new and more effective therapeutic approaches that aim to suppress ongoing autoimmune responses ...

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• Repair of Spinal Cord Injury (SCI) Using Bone Marrow Stromal Cell Transfected with Adenoviral Vector Expressing Glial derived Neurotropic Factor (GDNF) in a Rat SCI Model 

  Salarinia, R؛ Daei, A؛ Biglari, A؛ Jafari Anarkooli, I؛ Mazloomzadeh, S؛ Lowenstein, PR (Mashhad University of Medical Sciences, 2014-05-01)

  Back ground  Subsequent to spinal cord injury many pathological changes may occur that could lead to inappropriate environment for repair. The Most important of such changes is the death of neurons. Exogenous administration ...

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• Tissue Engineering in Dentistery 

  khajehahmadi, Saedeh (Mashhad University of Medical Sciences, 2014-05-01)

  Introduction Perforation of maxillary sinus mucous membrane is of the most prevalent complication during open sinus lift surgery. Moreover, such complication can usually be managed by an absorbable membrane. As far as ...

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• Different isolation methods of dental pulp stem cells 

  Pourgonabadi, Solmaz؛ Tayarani-Najaran, Zahra (Mashhad University of Medical Sciences, 2014-05-01)

  Considering the ease of isolation and high expansion potential of pulp stem/progenitor cells isolated from wisdom and primary teeth they have been implicated as the most reliable autologous cell source in dental tissue ...

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• Expressional Analysis of Stem Cell Marker SALL4 in Mesencephalon during Chicken Embryogenesis 

  Bahadori, Malihe؛ Zafar-Balannezjad, Saedeh؛ Forghanifard, Mohammad Mahdi (Mashhad University of Medical Sciences, 2014-05-01)

  Background SALL gene family represent a group of evolutionary conserved zinc finger transcription factors which are involved in normal development. It includes four members (SALL1 to SALL4). SALL4 has significant roles ...

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• The Effects of Low Level Laser Therapy on the Expression of Collagen Type I Gene and Proliferation of Human Gingival Fibroblasts (Hgf3-Pi 53): in vitro Study 

  Forouzanfar, Ali (Mashhad University of Medical Sciences, 2014-05-01)

  Background  Recent investigations show that both proliferation and secretion of macromolecules by cells can be regulated by low level laser therapy (LLLT). The aim of this study was to determine whether LLLT could induce ...

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• Rat Bone Marrow Mesenchymal Stem Cell Differentiation to Insulin Producing Cells and Evaluation their Responses in Vitro and in Vivo 

  Zojaj, Seyyed Abbas؛ Shafiee-Nick, Reza؛ Ghorbani, Ahmad (Mashhad University of Medical Sciences, 2014-05-01)

  Background  In recent years, many researchers haveattempted to cure diabetes by using stem cells technology. Stem cells from different sources have capabilityto differentiateinto insulin producing cells (IPCs) by different ...

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