• Agent Based Simulation of Sale and Manufacturing Agents Acting Across a Pharmaceutical Supply Chain 

  Pourghahreman, Narges؛ Rajabzadeh Ghatari, Ali؛ Moosivand, Asiye (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  Agent based modeling and simulation consider the behavior of agents acting in a system. The agents' interactions result in changing the agent's behavior, the whole agent based system, and its environment. In this study, ...

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• A Comparative Study on Different Pharmaceutical Industries and Proposing a Model for the Context of Iran 

  Safari, Hossein؛ Arab, Mohammad؛ Rashidian, Arash؛ Kebriaeezadeh, Abbas؛ Abolghasem Gorji, Hasan (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  Medication is known as the main and the most effective factor in improving public health. On the other hand, having a strong and effective pharmaceutical industry will, to a very large extent, guarantee people's health. ...

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• Aptamer-based Targeted Delivery of miRNA let-7d to Gastric Cancer Cells as a Novel Anti-Tumor Therapeutic Agent 

  Daei, Puyan؛ Ramezanpour, Mahsa؛ khanaki, korosh؛ Tabarzad, Maryam؛ Nikokar, Iraj؛ Hedayati CH, Mojtaba؛ Elmi, Ali (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  miRNAs as one of the potential therapeutic agents have been recently considered for cancer treatment. AS1411 (aptNCL) is a DNA aptamer specifically binding to nucleolin protein on the cancer cell surface with antiproliferative ...

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• Proteomics Applications in Health: Biomarker and Drug Discovery and Food Industry 

  Amiri dashatan, Nasrin؛ koushki, Mehdi؛ Abbaszadeh, Hojjat Allah؛ Rostami-Nejad, Mohammad؛ Rezaei Tavirani, Mostafa (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  Advancing in genome sequencing has greatly propelled the understanding of the living world, however, it is insufficient for full description of a biological system. Focusing on, proteomics has emerged as another large-scale ...

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• An approach to Improve Therapeutic Efficacy of Doxycycline Hyclate in Treatment of Periodontitis 

  Gorle, Ashish؛ Khairnar, Dinesh (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  A number of ways have been investigated for administration of antibacterial agents in dealing of plaque-initiated periodontal disease. These include prolonged release intrapocket devices which are inserted at diseased ...

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• Determination of Biological Activity of Recombinant Reteplase Using Clot Lysis Time and Activated Partial Thromboplastin Time (APTT) Lysis Methods: A Comparative Study 

  Babaee, Tahereh؛ Fazeli, Ahmad؛ Hashemi-Najafabadi, Sameereh؛ Rastegar, Hossein؛ Mohammadi, Ali؛ Khoshayand, Mohammadreza؛ Alebouyeh, M؛ fazeli, mohammad Reza (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  Recombinant plasminogen activator (reteplase) is a third generation thrombolytic agent which has been used on coronary artery thrombosis and acute myocardial infarction. Clot lysis assay is usually considered as a unique ...

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• Electrosprayed Nanosystems of Carbamazepine – PVP K30 for Enhancing Its Pharmacologic Effects 

  Abedinoghli, Deniz؛ Charkhpour, Mohammad؛ Osouli-Bostanabad, Karim؛ Selselehjonban, Sevil؛ Emami, Shahram؛ Barzegar-Jalali, Mohammad؛ adibkia, khosro (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  This study was conducted to enhance the pharmacologic effect of carbamazepine (CBZ) (as a poorly water-soluble drug) by fabricating CBZ-PVP K30 nanobeads using an electrospraying technique. CBZ-PVP K30 nanosystems with ...

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• First transcriptome analysis of Iranian scorpion, <i>Mesobuthus eupeus </i>venom gland 

  Baradaran, Masoumeh؛ Jalali, Amir؛ Naderi Soorki, Maryam؛ Jokar, Maumoud؛ Galehdari, Hamid (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  Scorpions are generally an important source of bioactive components, including toxins and other small peptides as attractive molecules for new drug development. Mesobuthus eupeus, from medically important and widely ...

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• Fingolimod Enhances Oligodendrocyte Differentiation of Transplanted Human Induced Pluripotent Stem Cell-Derived Neural Progenitors 

  Yazdi, Adadeh؛ Mokhtarzadeh Khanghahi, Akram؛ Baharvand, Hossein؛ Javan, Mohammad (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  Multiple sclerosis (MS) is an autoimmune disease which affects myelin in the central nervous system (CNS) and leads to serious disability. Currently available treatments for MS mainly suppress the immune system. Regenerative ...

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• Biological Monitoring of Healthcare Workers Exposed to Antineoplastic Drugs: Urinary Assessment of Cyclophosphamide and Ifosfamide 

  Baniasadi, Shadi؛ Alehashem, Maryam؛ Yunesian, Masud؛ Rastkari, Noushin (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  Exposure of health care workers to antineoplastic drugs and subsequent adverse health effects is still an open issue. Very little has been studied on the extent of occupational exposure and handling conditions of antineoplastic ...

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• Novel Colchicine Analogues Target Mitochondrial PT Pores Using Free Tubulins and Induce ROS-Mediated Apoptosis in Cancerous Lymphocytes 

  Aghvami, Marjan؛ Eshghi, Peyman؛ Zarei, Mohammad Hadi؛ Arefi, Hadi؛ Sattari, Fatemeh؛ Zarghi, Afshin؛ Pourahmad, Jalal (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  B-acute lymphoblastic leukemia (B-ALL) is the frequent pediatric malignity. Chemotherapy is the most practical approaches to deal with such malignancies. Microtubule-targeted agents are one of the most strategic drugs which ...

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• Biological Evaluation of the Isolated Compounds from Methanol fraction of<i> Leutea avicennia</i> Mozaff. 

  Sabernavaei, Mahsa؛ Kobarfard, Farzad؛ hadjiakhoondi, abbas؛ Aghaahmadi, Majid؛ Amin, Mohsen Amin؛ Yassa, Narguess (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  Leutea avicenniae Mozaff. belongs to Apiaceae family is an endemic species distributed in the west of Iran. The aim of this study was to investigate the antioxidant activity and acetylcholinestrase (AchE) inhibition of the ...

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• The effects of <i> Ocimum basilicum</i> extract and its constituent, rosmarinic acid on total and differential blood WBC, serum levels of NO, MDA, thiol, SOD, and CAT in ovalbumin sensitized rats 

  Eftekhar, Naeima؛ Moghimi, Ali؛ Boskabady, Mohammad Hossein (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  The effects of Ocimum basilicum (O. basilicum) and its constituent, rosmarinic acid, on total and differential blood WBC, serum levels of NO2, NO3, MDA, thiol, SOD and CAT in sensitized rats were examined. The study was ...

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• Effect of Losartan in Complete Freund’s Adjuvant –Induced Arthritis in Rats 

  Abed El -Gaphar, omnia؛ Abo youssef, Amira؛ Abo-Saif, Ali (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by joint infiltration and bone damage. The aim of the present study was to evaluate the beneficial effects of losartan in adjuvant-induced ...

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• Enhanced Production and Characterization of a Highly Stable Extracellular Protease from an Extreme Halophilic Isolate Salicola marasensis 

  Khoshnevis, Nika؛ Rezaei, Shahla؛ Samaei-Nouroozi, Amene؛ Amin, Mohsen؛ Moshfegh, Mahsa؛ Khoshayand, Mohammadreza؛ Faramarzi, Mohammad Ali (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  Owing to their superior catalytic activity in the extreme conditions, extremozymes have found the potential biotechnological applications for industrial purposes. A robust extracellular protease activity was detected in ...

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• Distinct effects of royal jelly on human endothelial cells under high glucose condition 

  Cheraghi, Omid؛ Abdollahpourasl, Mina؛ Rezabakhsh, aysa؛ Rahbarghazi, Reza (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  To assess different effects of royal Jelly in protecting the human endothelial cells from high glucose level, human umbilical vein endothelial cells were exposed to various concentrations of royal jelly, from 0.625 to 10 ...

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• Antibacterial and antitumor potential of actinomycetes isolated from mangrove soil in the Maowei Sea of the southern coast of China 

  Bin, Gong؛ Chen, Shuang؛ Nan, Wen؛ Zhu, Yan؛ Zhu, Cheng (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  Mangroves are the tidal forest existing in the intertidal zone and usually considered as the special marine ecosystem. In the present study, 452 actinomycetes were recovered from nine diferent sites at Maowei Sea Mangrove ...

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• Dihydroosajaxanthone: A New Natural Xanthone from the Branches of <i>Garcinia Schomburgkiana</i> Pierre 

  Meechai, Imron؛ phupong, worrapong؛ Chunglok, Warangkana؛ Meepowpan, Puttinan (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  Garcinia schomburgkiana, locally known in Thailand as an edible fruit “Ma-dan", is a plant species of the Clusiaceae family which has been reported as sources of a variety of compounds with biological activities. In the ...

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• Antitubercular Activity and Isolation of Chemical Constituents from plant <i>Vitex negundo</i> Linn. 

  Ladda, Padma؛ Magdum, Chandrakant (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  Tuberculosis still remains a leading cause of death in the world. Currently considerable interest in natural products and their derivatives in the area of drug research for multidrug resistant tuberculosis (MDR-TB). The ...

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• <i>Phenethyl isothiocyanate</i> Triggers Apoptosis, Combats Oxidative Stress and Inhibits Growth of Ehrlich Ascites Carcinoma Mouse Model 

  Eisa, Nada؛ Said, Heba؛ ElSherbiny, Nehal؛ Eissa, Laila؛ El-Shishtawy, Mamdouh (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2018-10-01)

  The aim of this study is to investigate the antitumor activity and possible molecular mechanism of Phenethyl isothiocyanate (PEITC) against Ehrlich ascites carcinoma in-vivo and in-vitro.In-vivo, ascetic fluid volume, body ...

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