• The Effect of Capital Structure on the Profitability of Pharmaceutical Companies The Case of Iran 

  Mohammadzadeh, Mehdi؛ Rahimi, Farimah؛ Rahimi, Forough؛ Aarabi, Seyed Mohammad؛ Salamzadeh, Jamshid (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Funding combination is the most important issue for the companies while they know the amount of required capital. Companies should be careful regarding the appliance of financial providing methods compatible with the ...

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• Maximizing Production of Human Interferon-γ in HCDC of Recombinant E. coli 

  Babaeipour, Valiollah؛ Shojaosadati, Seyed Abbas؛ Maghsoudi, Nader (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Tuning recombinant protein expression is an approach which can be successfully employed for increasing the yield of recombinant protein production in high cell density cultures. On the other hand, most of the previous ...

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• Impact of UGT1A9 Polymorphism on Mycophenolic Acid Pharmacokinetic Parameters in Stable Renal Transplant Patients 

  Mazidi, Talia؛ Rouini, Mohammad-Reza؛ Ghahremani, Mohammad-Hossein؛ Dashti-Khavidaki, Simin؛ Lessan-Pezeshki, Mahboob؛ Ahmadi, Farrokh lagha؛ Salam-Zadeh, Jamshid؛ Mandegary, Ali؛ Gholami, Kheirollah (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  There are wide individual differences in pharmacokinetic parameters of mycophenolate mofetil (MMF) among transplanted patients. Some studies have shown that single nucleotide polymorphisms (SNPs) of the Uridine Diphosphate ...

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• In-vitro Activity of 10 Antifungal Agents against 320 Dermatophyte Strains Using Microdilution Method in Tehran 

  Adimi, Parvaneh؛ Hashemi, Jamal؛ mahmoudi, mahmood؛ mirhndi, hossein؛ shidfar, mohammad reza؛ Emmami, Masood؛ Rezaei-Matehkolaei, Ali؛ Gramishoar, Mohsen؛ Kordbacheh, parivash (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Dermatophyte fungi are the etiologic agents of skin infections commonly referred to as ringworm. These infections are not dangerous but as a chronic cutaneous infections they may be difficult to treat and can also cause ...

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• Propranolol Prevents Osteoporosis and up-regulates Leptin in Ovariectomized Rats 

  Zhang, Xingguang؛ Lv, Xiaofeng؛ Zhang, Yanqi؛ Jiao, Xiumin؛ Chen, Bin (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Osteoporosis is a systemic skeletal disease and there is a close relationship between the sympathetic nervous system (SNS) and bone metabolism. Leptin has been shown to regulate bone formation and bone resorption via the ...

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• Study of Antidepressant and Sedative-HypnoticActivity of Hydroalcoholic Extract of Asperugo procumbens L. Aerial Parts in Mice 

  Mirshafa, Atefeh؛ Azadbakht, Mohammad؛ Ahangar, Nematollah (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Asperugo procumbens L. has been used in Iranian traditional medicine for the refreshing, tranquillizing and mood elevating activities. The present study was undertaken to evaluate the antidepressant and sedative-hypnotic ...

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• Evaluation of Antinociceptive Effect of Pregabalin in Mice and its Combination with Tramadol using Tail Flick Test 

  Keyhanfar, Fariborz؛ Shamsi Meymandi, Manzumeh؛ Sepehri, Gholamreza؛ Rastegaryanzadeh, Ramin؛ Heravi, Gioia (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  The development of combination therapy is a coherent approach in severe pain treatment. The present study investigated the antinociceptive effect of pregabalin alone and in combination with tramadol in acute pain modeling. ...

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• The Effect of Pentoxifylline on bcl-2 Gene Expression Changes in Hippocampus after Ischemia-Reperfusion in Wistar Rats by a Quatitative RT-PCR Method 

  Behzadi Andouhgerdi, Roudabeh؛ Hashemi, Mehrdad؛ Mahdian, Reza؛ parivar, kazem؛ Rezayat, Mehdi (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Ischemia-reperfusion injury is the tissue damage caused when blood supply returns to the tissue after a period of ischemia or lack of oxygen. Ischemia-reperfusion brain injury initiates an inflammatory response involving ...

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• Carbapenem restriction and its Effect on Bacterial Resistance in an Intensive Care unit of a Teaching Hospital 

  Sistanizad, Mohammad؛ Kouchek, Mehran؛ Miri, Mohammad؛ Goharani, Reza؛ Solouki, Mehrdad؛ Ayazkhoo, Ladan؛ Foroumand, Masoumeh؛ Mokhtari, Majid (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Development of antibiotic resistance in Intensive Care Units (ICUs) is a worldwide problem. The purpose of this study was to evaluate the effect of an antibiotic stewardship program (ASP) by carbapenems restriction on ...

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• Sub-chronic Dermal Toxicity of Silver Nanoparticles in Guinea Pig: Special Emphasis to Heart, Bone and Kidney Toxicities 

  Korani, Mitra؛ Rezayat, Mehdi؛ Arbabi, Sepideh (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Silver nanoparticles (Ag NPs) have been widely used as new potent antimicrobial agents in cosmetic and hygienic products. Present study compares the tissue levels of Ag NPs in different organs of Guiana Pigs quantitatively ...

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• Development and use a Novel Combined In-vivo and In-vitro Assay for Anti-inflammatory and Immunosuppressive Agents 

  li, tan؛ chen, hong؛ mei, xin؛ wei, na؛ cao, bo (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Contact hypersensitivity (CHS) mouse model induced by 2, 4-dinitrofluorobenzene (DNFB) is thought to be a T helper 1 (Th1)-dominant response and used for investigating anti-inflammatory and immunosuppressive agents. However, ...

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• Fragment-based Binding Efficiency Indices in Bioactive Molecular Design: A Computational Approach to BACE-1 Inhibitors 

  Razzaghi-Asl, Nima؛ ebadi, ahmad؛ Edraki, Najmeh؛ Shahabipour, Sara؛ Miri, Ramin (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  One of the most important targets in Alzheimer disease is Beta site amyloid precursor protein cleaving enzyme-1 (BACE-1). It is a membrane associated protein and is one of the main enzymes responsible for amyloid β (Aβ) ...

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• Application of Taguchi Design and Response Surface Methodology for Improving Conversion of Isoeugenol into Vanillin by Resting Cells of Psychrobacter sp. CSW4 

  Ashengroph, morahem؛ Nahvi, Iraj؛ Amini, Jahanshir (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  For all industrial processes, modelling, optimisation and control are the keys to enhance productivity and ensure product quality. In the current study, the optimization of process parameters for improving the conversion ...

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• Intrahippocampal Injection of 3α Diol (a Testosterone Metabolite ) and Indomethacin (3α-HSD Blocker), Impair Acquisition of Spatial Learning and Memory in Adult Male Rats 

  Assadian Narenji, Somayeh؛ Naghdi, Nasser؛ Oryan‏, Shahrbanoo؛ Azadmanesh, Keyhan (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Hippocampus is essentially involved in learning and memory processes, and is known to be a target for androgen actions. The high density of the androgen receptors in hippocampus shows that there must be some relationship ...

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• Biological Evaluation of a Siliconized Analog of Clofibrate (Silafibrate) in Rodents 

  Ziaee, Mojtaba؛ Eghbal, Mohammad-ali؛ Rahmani kahnamoei, Jafar؛ Ghaffarzadeh, Mohammad؛ Bolourtchian, Mohammad؛ Khorrami, Arash؛ Garjani, Alireza (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Silicon is the element very similar to carbon, and bioactive siliconized compounds have therefore received much attention. Siliconization of a compound enhances its biological activities. In the present study the hypolipidemic ...

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• Endothelium-dependent Effect of Sesame Seed Feeding on Vascular Reactivity of Streptozotocin-diabetic Rats: Underlying Mechanisms 

  Roghani, Mehrdad؛ Jalali Nadoushan, Mohammad Reza؛ Baluchnejadmojarad, Tourandokht؛ Vaez Mahdavi, Mohammad Reza؛ Naderi, Gholamali؛ Roghani Dehkordi, Farshad؛ Joghataei, Mohammad Taghi (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Cardiovascular disorders continue to constitute major causes of morbidity and mortality in diabetic patients. In this study, the effect of chronic administration of sesame (Sesamum indicum L) seed feeding was studied on ...

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• Umbelliprenin from Ferula szowitsiana Activates both Intrinsic and Extrinsic Pathways of Apoptosis in Jurkat T-CLL Cell Line 

  gholami, omid؛ Jeddi-Tehrani, Mahmood؛ Iranshahi, Mehrdad؛ Zarnani, Amir Hasan؛ ziai, Seyed Ali (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Umbelliprenin is a prenylated compound, which belongs to the class of sesquiterpene coumarins. It is extracted from dried roots of Ferula szwitsiana collected from the mountains of Golestan forest (Golestan Province, north ...

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• Inhibitory Effect of Black and Red Pepper and Thyme Extracts and Essential Oils on Enterohemorrhagic Escherichia coli and DNase Activity of Staphylococcus aureus 

  Zarringhalam, Maryam؛ Zarringhalam, Jalal؛ shadnoush, mahdi؛ Rezazadeh, Shamsali؛ Tekieh, Elaheh (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  In this study, extracts and essential oils of Black and Red pepper and Thyme were tested for antibacterial activity against Escherichia coli O157:H7 andStaphylococcus aureus. Black and Red pepper and Thyme were provided ...

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• Hypoglycemic Effects of Three Medicinal Plants in Experimental Diabetes: Inhibition of Rat Intestinal α-glucosidase and Enhanced Pancreatic Insulin and Cardiac Glut-4 mRNAs Expression 

  moradabadi, leila؛ montasser kouhsari, Shideh؛ Fehresti Sani, Mohammad (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Garlic (Allium sativum L., Alliaceae), Persian shallot (Allium ascalonicum L., Alliaceae ) and Sage (Salvia officinalis L., Lamiaceae) are believed to have hypoglycemic properties and have been used traditionally as ...

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• Virtual Screening Analysis and In-vitro Xanthine Oxidase Inhibitory Activity of Some Commercially Available Flavonoids 

  Umamaheswari, Muthuswamy؛ MADESWARAN, ARUMUGAM؛ AsokKumar, Kuppusamy؛ PARAMESHWARAN, SIVA؛ Subhadradevi, Varadharajan؛ Jagannath, Puliyath (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2013-09-01)

  Allopurinol, the xanthine oxidase inhibitor, is the only drug available for the treatment of gout. We examined the xanthine oxidase inhibitory activity of some commercially available flavonoids such asepigallocatechin, ...

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