Volume 15, Issue 17
مرور بر اساس
ارسال های اخیر
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Possible Cancer Formation Mechanisms - View at the Cellular Level
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)
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SCYL1BP1 has Tumor-suppressive Functions in Human Lung Squamous Carcinoma Cells by Regulating Degradation of MDM2
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)SCY1-like 1-binding protein 1 (SCYL1BP1) is a newly identified transcriptional activator domain containing protein with many unknown biological functions. Recently emerging evidence has revealed that it is a novel regulator ...
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Clinical Investigation of Efficacy of Albumin Bound Paclitaxel plus Platinum Compounds as First-line Chemotherapy for Stage Ⅲ/IV Squamous Non-small Cell Lung Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Objective: To observe the efficacy and toxicity of nanoparticle albumin bound paclitaxel (nab-paclitaxel) plus platinum agent (cisplatin or carboplatin) as first line treatment for stage III/IV squamous ...
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Correlation of Contrast-Enhanced Ultrasonographic Features with Microvessel Density in Papillary Thyroid Carcinomas
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: The purpose of this study was to investigate the correlation of contrast-enhanced ultrasonographic (CEUS) features with microvessel density (MVD) in papillary thyroid carcinomas (PTCs). Materials and ...
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XRCC1 Gene Polymorphism, Diet and Risk of Colorectal Cancer in Thailand
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Colorectal cancer (CRC) is one of the most common cancers worldwide. This study aimed to investigate the interaction between the presence of a polymorphism of the XRCC1 gene and known risk factors for ...
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ABO Blood Group, Epstein-Barr virus Infection and Prognosis of Patients with Non-metastatic Nasopharyngeal Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: A prior study showed blood type A/AB to be associated with an increased risk of nasopharyngeal carcinoma (NPC) compared to subjects with blood type O. However, the relationship between ABO blood groups ...
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In vitro and In vivo Antitumor Activity of Tiliacorinine in Human Cholangiocarcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Cholangiocarcinoma (CCA) is a fatal cancer with poor prognosis and less than 10% of CCA patients can be offered surgical cure. Conventional chemotherapy results in unfavorable outcomes. At present, plant-derived compounds ...
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Effects of p53 Codon 72 and MDM2 SNP309 Polymorphisms on Gastric Cancer Risk among the Iranian Population
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Development of gastric cancer (GC) is a multistep process that requires alterations in the expression of oncogenes and tumor suppressor genes, occurring over several decades. The p53 tumor suppressor ...
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Acceptability of Self-Sampling HPV Testing Among Thai Women for Cervical Cancer Screening
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Acceptability of self-sampling HPV testing is confirmed worldwide. However, some cultural differences may affect this question. Therefore, this study was conducted to evaluate the acceptability of ...
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Tobacco Smoke Exposure and Breast Cancer Risk in Thai Urban Females
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)The incidence of urban female breast cancer has been continuously increasing over the past decade with unknown etiology. One hypothesis for this increase is carcinogen exposure from tobacco. Therefore, the objective of ...
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Exploratory Investigation of Genetic Associations with Basal Cell Carcinoma Risk: Genome-Wide Association Study in Jeju Island, Korea
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Aim: Little is known about the genetic associations with Basal cell carcinoma (BCC) risk in non-Caucasian populations, in which BCC is rare, as in Korea. We here conducted a pilot genome-wide association study (GWAS) in ...
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Association between the XRCC1 Arg194Trp Polymorphism and Glioma Risk: an Updated Meta-analysis
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Gliomas are the most common type of primary brain tumors. The XRCC1 Arg194Trp variant affects the proliferating cell nuclear antigen( PCNA) binding region, which suggests that this mutation may contribute to gliomagenesis ...
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Diagnostic Values of Serum Levels of Pepsinogens and Gastrin-17 for Screening Gastritis and Gastric Cancer in a High Risk Area in Northern Iran
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Gastric cancer (GC) is the second cause of cancer related death in the world. It may develop by progression from its precancerous condition, called gastric atrophy (GA) due to gastritis. The aim of this ...
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Elevated Expression of Nuclear Protein Kinase CK2α as a Poor Prognosis Indicator in Lymph Node Cancerous Metastases of Human Thyroid Cancers
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Aim: To investigate the expression of protein kinase CK2α (CK2α) in human thyroid disease and its relationship with thyroid cancer metastasis. Materials and Methods: Using immunohistochemistry we measured the ...
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Isomeric Folate-Conjugated Polymeric Micelles Bind to Folate Receptors and Display Anticancer Effects
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)The present study aimed to prepare and evaluate polymeric micelles conjugated with folic acid through α- or γ-carboxyl groups for antitumor efficacy. The isomeric block copolymers, α- and γ-folate-polyethyleneglycol–distearoyl ...
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A Novel Mutant of Human Papillomavirus Type 18 E6E7 Fusion Gene and its Transforming Activity
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Persistent human papillomavirus (HPV) infection, especially with high-risk types such as HPV16 and HPV18, has been identified as the primary cause of cervical cancer. E6 and E7 are the major onco-proteins ...
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Comparison of 2-Dimensional and 3-Dimensional Conformal Treatment Plans in Gastric Cancer Radiotherapy
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Postoperative chemoradiotherapy is accepted as standard treatment for stage IB-IV, M0 gastric cancer. Radiotherapy (RT) planning of gastric cancer is important because of the low radiation tolerance of ...
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Significant Genotype Difference in the CYP2E1 PstI Polymorphism of Indigenous Groups in Sabah, Malaysia with Asian and Non-Asian Populations
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)CYP2E1 PstI polymorphism G-1259C (rs3813867) genotype distributions vary significantly among different populations and are associated with both diseases, like cancer, and adverse drug effects. To date, there have been ...
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Pu-erh Tea Powder Preventive Effects on Cisplatin-Induced Liver Oxidative Damage in Wistar Rats
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Chemotherapy is one of the major means for control of malignancies, with cisplatin (CDDP) as one of the main agents, widely used for the treatment of various malignant solid tumors. However, prevention ...
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Evaluation of the Radiation Pneumonia Development Risk in Lung Cancer Cases
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Concurrent chemo-radiotherapy is the recommended standard treatment modality for patients with locally advanced lung cancer. The purpose of three-dimensional conformal radiotherapy (3DCRT) is to minimize ...
