Volume 15, Issue 17
مرور بر اساس
ارسال های اخیر
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Correlation of Contrast-Enhanced Ultrasonographic Features with Microvessel Density in Papillary Thyroid Carcinomas
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: The purpose of this study was to investigate the correlation of contrast-enhanced ultrasonographic (CEUS) features with microvessel density (MVD) in papillary thyroid carcinomas (PTCs). Materials and ...
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SCYL1BP1 has Tumor-suppressive Functions in Human Lung Squamous Carcinoma Cells by Regulating Degradation of MDM2
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)SCY1-like 1-binding protein 1 (SCYL1BP1) is a newly identified transcriptional activator domain containing protein with many unknown biological functions. Recently emerging evidence has revealed that it is a novel regulator ...
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In vitro and In vivo Antitumor Activity of Tiliacorinine in Human Cholangiocarcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Cholangiocarcinoma (CCA) is a fatal cancer with poor prognosis and less than 10% of CCA patients can be offered surgical cure. Conventional chemotherapy results in unfavorable outcomes. At present, plant-derived compounds ...
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ABO Blood Group, Epstein-Barr virus Infection and Prognosis of Patients with Non-metastatic Nasopharyngeal Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: A prior study showed blood type A/AB to be associated with an increased risk of nasopharyngeal carcinoma (NPC) compared to subjects with blood type O. However, the relationship between ABO blood groups ...
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XRCC1 Gene Polymorphism, Diet and Risk of Colorectal Cancer in Thailand
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Colorectal cancer (CRC) is one of the most common cancers worldwide. This study aimed to investigate the interaction between the presence of a polymorphism of the XRCC1 gene and known risk factors for ...
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Tobacco Smoke Exposure and Breast Cancer Risk in Thai Urban Females
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)The incidence of urban female breast cancer has been continuously increasing over the past decade with unknown etiology. One hypothesis for this increase is carcinogen exposure from tobacco. Therefore, the objective of ...
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Association between the XRCC1 Arg194Trp Polymorphism and Glioma Risk: an Updated Meta-analysis
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Gliomas are the most common type of primary brain tumors. The XRCC1 Arg194Trp variant affects the proliferating cell nuclear antigen( PCNA) binding region, which suggests that this mutation may contribute to gliomagenesis ...
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Exploratory Investigation of Genetic Associations with Basal Cell Carcinoma Risk: Genome-Wide Association Study in Jeju Island, Korea
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Aim: Little is known about the genetic associations with Basal cell carcinoma (BCC) risk in non-Caucasian populations, in which BCC is rare, as in Korea. We here conducted a pilot genome-wide association study (GWAS) in ...
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Elevated Expression of Nuclear Protein Kinase CK2α as a Poor Prognosis Indicator in Lymph Node Cancerous Metastases of Human Thyroid Cancers
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Aim: To investigate the expression of protein kinase CK2α (CK2α) in human thyroid disease and its relationship with thyroid cancer metastasis. Materials and Methods: Using immunohistochemistry we measured the ...
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Residual Disease Following Conization of Women with Stage IA-IB1 Cervical Carcinoma in a High Incidence Region
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: To determine rates of residual disease along with influencing factors in women with stage IA to IB1 cervical carcinoma after conization. Materials and Methods: A retrospective study was ...
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Significant Genotype Difference in the CYP2E1 PstI Polymorphism of Indigenous Groups in Sabah, Malaysia with Asian and Non-Asian Populations
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)CYP2E1 PstI polymorphism G-1259C (rs3813867) genotype distributions vary significantly among different populations and are associated with both diseases, like cancer, and adverse drug effects. To date, there have been ...
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Evaluation of the Radiation Pneumonia Development Risk in Lung Cancer Cases
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Concurrent chemo-radiotherapy is the recommended standard treatment modality for patients with locally advanced lung cancer. The purpose of three-dimensional conformal radiotherapy (3DCRT) is to minimize ...
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Pu-erh Tea Powder Preventive Effects on Cisplatin-Induced Liver Oxidative Damage in Wistar Rats
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Chemotherapy is one of the major means for control of malignancies, with cisplatin (CDDP) as one of the main agents, widely used for the treatment of various malignant solid tumors. However, prevention ...
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Isomeric Folate-Conjugated Polymeric Micelles Bind to Folate Receptors and Display Anticancer Effects
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)The present study aimed to prepare and evaluate polymeric micelles conjugated with folic acid through α- or γ-carboxyl groups for antitumor efficacy. The isomeric block copolymers, α- and γ-folate-polyethyleneglycol–distearoyl ...
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Elevated Neutrophil-to-Lymphocyte Ratio in Squamous Cell Carcinoma of Larynx Compared to Benign and Precancerous Laryngeal Lesions
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: Laryngeal carcinogenesis is a multifactorial process that has not been fully elucidated. Despite extensive research, reliable markers with diagnostic and prognostic value are still lacking. It was recently ...
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Association between Circulating Vitamin D, the Taq1 Vitamin D Receptor Gene Polymorphism and Colorectal Cancer Risk among Jordanians
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: The physiological role of vitamin D extends beyond bone health and calcium-phosphate homeostasis to effects on cancer risk, mainly for colorectal cancer. Vitamin D may have an anticancer effect in ...
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Prognostic Model Built on Blood-based Biomarkers in Patients with Metastatic Colorectal Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Background: We had previously showed that the neutrophil lymphocyte ratio (NLR), γ-glutamyl transpeptidase (GGT) and carcinoembryonic antigen (CEA) are prognostic factors for metastatic colorectal cancer (mCRC) ...
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Stratification Analysis and Case-control Study of Relationships between Interleukin-6 Gene Polymorphisms and Cervical Cancer Risk in a Chinese Population
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Interleukin-6 (IL-6), a central proinflammatory cytokine, maintains immune homeostasis and also plays important roles in cervical cancer. Therefore, we aimed to evaluate any associations of IL-6 gene polymorphisms at ...
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Prevalence and Genotype Distribution of Human Papillomavirus among Women from Henan, China
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Human papillomavirus (HPV) infection has been implicated as a causative of cervical cancer. In the present study, a total of 578 samples from females attending the gynecological outpatient clinic in Henan province, China,were ...
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Expression of ERCC1, RRM1 and LRP in Non-small Cell Lung Cancers and their Influence on Chemotherapeutic Efficacy of Gemcitabine Concomitant with Nedaplatin
(West Asia Organization for Cancer Prevention (WAOCP), 2014-12-01)Objective: To explore the clinical efficacy of gemcitabine concomitant with nedaplatin and drug resistance in the treatment of non-small cell lung cancer (NSCLC) and associated molecular predicators. Materials ...
