Volume 20, Issue 11
مرور بر اساس
ارسال های اخیر
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Identification of Mutation in Exon11 of BRCA1 Gene in Bangladeshi Patients with Breast Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Background: Worldwide, breast cancer is the leading cause of cancer death in female, in Bangladesh breast cancer is the second leading cancer in both sexes, and in women it occupied the top position. Highly penetrant ...
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Value of CIM, CLO Test and Multiplex PCR for the Diagnosis of Helicobacter Pylori Infection Status in Patients with Gastritis and Gastric Ulcer
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Objective: To assess the value of Current Infection Marker (CIM) test, Campylobacter-Like Organism (CLO) test, and the multiplex polymerase chain reaction test (PCR) for the diagnosis of Helicobacter pylori (H. pylori) ...
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Histological Sampling of Endometrial Tissue: Comparison between the MedGyn® Endosampler and Formal Fractional Curettage in Patients with Abnormal Uterine Bleeding
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Background: Several methods have been used for evaluation of the endometrial pathology in patients with abnormal uterine bleeding. Endometrial biopsy is one of the primary methods used for diagnostic evaluation, which is ...
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Design, Synthesis and Biological Evaluation of Benzo[D]Thiazole with Dimethylpyrazol Derivatives
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)A series of new benzothiazole derivatives containing dimethylpyrazole were synthesized and evaluated for their anticonvulsant activity, neurotoxicity and cytotoxicity by using the maximal electroshock (MES), rotarod ...
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Deep Convolution Neural Network for Malignancy Detection and Classification in Microscopic Uterine Cervix Cell Images
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Objective: Automated Pap smear cervical screening is one of the most effective imaging based cancer detection tools used for categorizing cervical cell images as normal and abnormal. Traditional classification methods ...
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An Investigation on the Therapeutic Potential of Butein, A Tretrahydroxychalcone Against Human Oral Squamous Cell Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Background: Oral squamous cell carcinoma (OSCC) is one of the most predominant cancers in India. With advances in the field of oncology, a number of therapies have emerged; however, they are minimally effective. Consequently, ...
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Implication of Soluble HLA-G and HLA-G +3142G/C Polymorphism in Breast Cancer Patients Receiving Adjuvant Therapy in Tanzania
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Background: During cancer growth, immunosuppressive microenvironment is created that enables tumour cells to evade an eliminative immune response and hence manage to grow into malignancy. HLA-G, existing as either ...
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Investigating the effect of Integrated Educational Program on the Quality of Life among Cancer Patients: A Clinical Trial Study
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Background: cancer is one of the most common causes of death around the world. The process of this disease and the resulting complications reduce the quality of life of cancer patients. Taking the necessary measures for ...
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Repurposing Drugs by In Silico Methods to Target BCR Kinase Domain in Chronic Myeloid Leukemia
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Background: Targeted therapy in the form of highly selective tyrosine kinase inhibitors (TKIs) has transformed the treatment of chronic myeloid leukemia (CML). However, mutations in the kinase domain contribute to drug ...
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Characterization of High-risk Oncogenic Human Papillomavirus Genotypes in Histologically Confirmed Ear, Nose and Throat (Ent) Cancers in Burkina Faso
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Background: High-risk human papillomavirus (HPV-HR) infections are responsible for 99.99% of cervico-uterine cancers and 50% of carcinomas of the oropharynx. Objective: To characterize high-risk HPV genotypes (HPV-HR) in ...
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Increased CD8 Tumor Infiltrating Lymphocytes in Colorectal Cancer Microenvironment Supports an Adaptive Immune Resistance Mechanism of PD-L1 Expression
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Background: Tumor cells express programmed death ligand-1 (PD-L1) through several biological processes, thereby having different clinical significance depending on the underlying mechanism of expression. Currently, mechanisms ...
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Cofactors and Their Association with Cancer of the Uterine Cervix in Women Infected with High-Risk Human Papillomavirus in South India
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Background: Human papilloma viruses (HPVs) are recognized as the major etiological agents of most pre invasive and invasive cancer of the uterine cervix. Many cofactors in association with high-risk HPV (HR-HPV) trigger ...
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The Effectiveness of Smoking Prevention Module Towards Knowledge and Smoking Refusal Skills among Adolescents in Kota Bharu, Kelantan, Malaysia
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Objective: To study the effectiveness of the smoking prevention module towards knowledge on smoking and its harmful effects and smoking refusal skills among secondary school students in Kelantan, Malaysia. Methods: A quasi ...
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Predictive Value of Neutrophil to Lymphocyte Ratio in the Diagnosis of Significant Prostate Cancer at Initial Biopsy: A Comparison with Free Percent Prostate Specific Antigen, Prostate Specific Antigen Density and Primary Circulating Prostate Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Introduction: An elevated serum PSA is the only biomarker routinely used in screening for prostate cancer to indicate a prostate biopsy. However, it is not specific for prostate cancer and the neutrophil/lymphocyte ratio ...
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Improved Outcomes of Childhood Acute Lymphoblastic Leukemia: A Retrospective Single Center Study in Saudi Arabia
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Objective: Understanding the clinical and genetic characteristics of pediatric acute lymphoblastic leukemia (ALL) patients may help assigning the appropriate treatment. This study aims to understand patients' ...
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Up-Regulation of MiRNA-125a-5p Inhibits Cell Proliferation and Increases EGFR-TKI Induced Apoptosis in Lung Cancer Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Background: Despite the dramatic efficacy of erlotinib, an EGFR tyrosine kinase inhibitor (TKI), most of non-small cell lung cancer (NSCLC) patients ultimately acquire resistance to this agent. Different studies indicated ...
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Association between C1236T Genetic Variant of ABCB1 Gene and Molecular Response to Imatinib in Indonesian Chronic Myeloid Patients
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Objective: Imatinib is the first-line drug used for the treatment of chronic myeloid leukemia (CML) patients due to high molecular response and overall survival rate. However, some patients develop resistance to imatinib ...
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Mdm2-P53 Interaction Inhibitor with Cisplatin Enhances Apoptosis in Colon and Prostate Cancer Cells In-Vitro
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Objective: To study the effect of RITA (MDM2-p53 interaction inhibitor) and its action along with genotoxic drug cisplatin was evaluated on COLO-205 colon cancer and PC-3 prostate cancer cells. Method: Various in-vitro ...
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Explaining Perceived Priorities in Women with Breast Cancer: A Qualitative Study
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Objective: Cancer is a stressful event in life, and the dreadful impact and problems created for patients and families by cancer negatively affect their quality of life. Therefore, regarding the increasing number of ...
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Pharmacological Characterization and Raman Spectroscopy Evaluation of Oral and Maxillofacial Surgery-Related Carnoy´S Solution Modified by Different Viscosity Agents
(West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)Background: There are several lesions of odontogenic and non-odontogenic origin in the oral cavity, such as odontogenic keratocyst, as well as many treatment options for such lesions. In order to reduce recurrence due to ...



