• Histological Sampling of Endometrial Tissue: Comparison between the MedGyn® Endosampler and Formal Fractional Curettage in Patients with Abnormal Uterine Bleeding 

  Tumrongkunagon, Sirichoke؛ Suknikhom, Wineeya (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Background: Several methods have been used for evaluation of the endometrial pathology in patients with abnormal uterine bleeding. Endometrial biopsy is one of the primary methods used for diagnostic evaluation, which is ...

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• Nasopharyngeal Carcinoma (NPC) Risk Factors: A Systematic Review and Meta-Analysis of the Association with Lifestyle, Diets, Socioeconomic and Sociodemographic in Asian Region 

  Okekpa, Simon I؛ S M N Mydin, Rabiatul Basria؛ Mangantig, Ernest؛ Azmi, Nor Syaffaf Amaliana؛ Zahari, Siti Nur Syahirah؛ Kaur, Gurjeet؛ Musa, Yusri (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Objective: Risk factors of nasopharyngeal carcinoma (NPC) have been linked with diets, life style and viral infections. NPC is more rampant in Asian populations than non-Asian countries. Our study aims to assess the ...

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• Association between Cyclooxygenase-2 and Indoleamine 2,3-Dioxygenase Expression in Breast Cancer Patients from Pakistan 

  Asghar, Kashif؛ Loya, Asif؛ Rana, Iftikhar Ali؛ Abu Bakar, Muhammad؛ Farooq, Asim؛ Tahseen, Muhammad؛ Ishaq, Muhammad؛ Rashid, Muhammad Usman (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Background: Tumors use several immunosuppressive mechanisms to evade immune destruction. Cyclooxygenase-2 (COX-2) expression may be a driver of immunosuppression in breast cancer, but the mechanisms involved remain elusive. ...

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• Design, Synthesis and Biological Evaluation of Benzo[D]Thiazole with Dimethylpyrazol Derivatives 

  Liu, Dachuan؛ Cheng, Xiu؛ Wang, Ying (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  A series of new benzothiazole derivatives containing dimethylpyrazole were synthesized and evaluated for their anticonvulsant activity, neurotoxicity and cytotoxicity by using the maximal electroshock (MES), rotarod ...

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• Identification of Mutation in Exon11 of BRCA1 Gene in Bangladeshi Patients with Breast Cancer 

  Nishat, Latifa؛ Yesmin, Zinnat Ara؛ Arjuman, Farida؛ Rahman, Sufi Hannan Zulfiqar؛ Banu, Laila Anjuman (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Background: Worldwide, breast cancer is the leading cause of cancer death in female, in Bangladesh breast cancer is the second leading cancer in both sexes, and in women it occupied the top position. Highly penetrant ...

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• Value of CIM, CLO Test and Multiplex PCR for the Diagnosis of Helicobacter Pylori Infection Status in Patients with Gastritis and Gastric Ulcer 

  Trung, Tran Thien؛ Minh, Tran Anh؛ Anh, Nguyen Tuan (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Objective: To assess the value of Current Infection Marker (CIM) test, Campylobacter-Like Organism (CLO) test, and the multiplex polymerase chain reaction test (PCR) for the diagnosis of Helicobacter pylori (H. pylori) ...

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• An Investigation on the Therapeutic Potential of Butein, A Tretrahydroxychalcone Against Human Oral Squamous Cell Carcinoma 

  Bordoloi, Devivasha؛ Monisha, Javadi؛ Roy, Nand Kishor؛ Padmavathi, Ganesan؛ Banik, Kishore؛ Harsha, Choudhary؛ Wang, Hong؛ Kumar, Alan Prem؛ Arfuso, Frank؛ Kunnumakkara, Ajaikumar (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Background: Oral squamous cell carcinoma (OSCC) is one of the most predominant cancers in India. With advances in the field of oncology, a number of therapies have emerged; however, they are minimally effective. Consequently, ...

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• Quality Assessment of Websites Providing Information on Human Papillomavirus Vaccines in Thailand 

  Likitdee, Naratassapol؛ Jampathong, Nampet؛ Kietpeerakool, Chumnan (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Objectives: To assess the quality of websites that provide information about human papillomavirus (HPV) vaccination using the criteria laid out by the World Health Organization Global Advisory Committee on Vaccine Safety. ...

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• Association of MicroRNA 196a and 499 Polymorphisms with Development of Cirrhosis and Hepatocellular Carcinoma Post-HCV Infection in Egyptian Patients 

  Fteah, Asmaa Mohamed؛ Ahmed, Asmaa Ismail؛ Mosaad, Nehad Ahmed؛ Hassan, Mona Mohamed؛ Mahmoud, Sherif Hamdy (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Hepatocellular carcinoma (HCC) is the commonest primary tumor of the liver. Chronic HCV infection is the leading cause of end-stage liver disease, HCC and liver-related death in Egypt. Single nucleotide polymorphisms (SNPs) ...

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• Investigating the effect of Integrated Educational Program on the Quality of Life among Cancer Patients: A Clinical Trial Study 

  Bayati, Maryam؛ Molavynejad, Shahram؛ Taheri, Norollah؛ Cheraghian, Bahman (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Background: cancer is one of the most common causes of death around the world. The process of this disease and the resulting complications reduce the quality of life of cancer patients. Taking the necessary measures for ...

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• Implication of Soluble HLA-G and HLA-G +3142G/C Polymorphism in Breast Cancer Patients Receiving Adjuvant Therapy in Tanzania 

  Adolf, Ismael Chatita؛ Akan, Gokce؛ Mselle, Teddy F؛ Dharsee, Nazima؛ Namkinga, Lucy A؛ Atalar, Fatmahan (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Background: During cancer growth, immunosuppressive microenvironment is created that enables tumour cells to evade an eliminative immune response and hence manage to grow into malignancy. HLA-G, existing as either ...

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• Deep Convolution Neural Network for Malignancy Detection and Classification in Microscopic Uterine Cervix Cell Images 

  P B, Shanthi؛ Faruqi, Faraz؛ K S, Hareesha؛ Kudva, Ranjini (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Objective: Automated Pap smear cervical screening is one of the most effective imaging based cancer detection tools used for categorizing cervical cell images as normal and abnormal. Traditional classification methods ...

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• Increased CD8 Tumor Infiltrating Lymphocytes in Colorectal Cancer Microenvironment Supports an Adaptive Immune Resistance Mechanism of PD-L1 Expression 

  Sudoyo, Aru W؛ Kurniawan, Antonius N؛ Kusumo, Gita D؛ Putra, Teguh P؛ Rexana, Fritzie A؛ Yunus, Muhammad؛ Budiyati, Akterono D؛ Kurniawan, Dicky؛ Utama, Andi؛ Utomo, Ahmad R (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Background: Tumor cells express programmed death ligand-1 (PD-L1) through several biological processes, thereby having different clinical significance depending on the underlying mechanism of expression. Currently, mechanisms ...

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• Comparative Analysis between the Gail, Tyrer-Cuzick and BRCAPRO Models for Breast Cancer Screening in Brazilian Population 

  Stevanato, Kely Paviani؛ Pedroso, Raíssa Bocchi؛ Iora, Pedro؛ Santos, Lander dos؛ Pelloso, Fernando Castilho؛ Melo, Willian Augusto de؛ Carvalho, Maria Dalva de Barros؛ Pelloso, Sandra Marisa (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Objective: To analyze the diagnostic accuracy of predictive models of breast cancer risk for the Brazilian population. Method: A cross-sectional, study was conducted in a sample of 382 women aged 35-69 years who were users ...

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• Cofactors and Their Association with Cancer of the Uterine Cervix in Women Infected with High-Risk Human Papillomavirus in South India 

  Baskran, Krishnan؛ Kumar, P Kranthi؛ Santha, K؛ Sivakamasundari, Inmozhi i (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Background: Human papilloma viruses (HPVs) are recognized as the major etiological agents of most pre invasive and invasive cancer of the uterine cervix. Many cofactors in association with high-risk HPV (HR-HPV) trigger ...

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• Characterization of High-risk Oncogenic Human Papillomavirus Genotypes in Histologically Confirmed Ear, Nose and Throat (Ent) Cancers in Burkina Faso 

  Ilboudo, Maïmouna؛ Zohoncon, Théodora Mahoukèdè؛ Traore, Esther Mah Alima؛ Traore, Ina Marie Angèle؛ Kande, Ali؛ Djigma, Florencia W؛ Obiri-Yeboah, Dorcas؛ Gyebre, Yvette Marie Chantal؛ Simpore, Jacques (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Background: High-risk human papillomavirus (HPV-HR) infections are responsible for 99.99% of cervico-uterine cancers and 50% of carcinomas of the oropharynx. Objective: To characterize high-risk HPV genotypes (HPV-HR) in ...

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• Repurposing Drugs by In Silico Methods to Target BCR Kinase Domain in Chronic Myeloid Leukemia 

  Natarajan, Aparna؛ Thangarajan, Rajkumar؛ Kesavan, Sabitha (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Background: Targeted therapy in the form of highly selective tyrosine kinase inhibitors (TKIs) has transformed the treatment of chronic myeloid leukemia (CML). However, mutations in the kinase domain contribute to drug ...

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• Predictive Value of Neutrophil to Lymphocyte Ratio in the Diagnosis of Significant Prostate Cancer at Initial Biopsy: A Comparison with Free Percent Prostate Specific Antigen, Prostate Specific Antigen Density and Primary Circulating Prostate Cells 

  Murray, Nigel P؛ Fuentealba, Cynthia؛ Reyes, Eduardo؛ Lopez, Marco Antonio؛ Salazar, Anibal؛ Minzer, Simona؛ Munoz, Lorena؛ Orrego, Shenda؛ Guzman, Eghon؛ Arzeno, Lucas (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Introduction: An elevated serum PSA is the only biomarker routinely used in screening for prostate cancer to indicate a prostate biopsy. However, it is not specific for prostate cancer and the neutrophil/lymphocyte ratio ...

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• The Role of the LY294002 - A Non-Selective Inhibitor of Phosphatidylinositol 3-Kinase (PI3K) Pathway- in Cell Survival and Proliferation in Cell Line SCC-25 

  Duarte, Andressa؛ Silveira, Giórgia Gobbi؛ Soave, Danilo Figueiredo؛ Costa, João Paulo Oliveira؛ Silva, Alfredo Ribeiro (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  The activation of PI3K further activates subsequent regulatory pathways, which are activated via AKT phosphorylation. AKT is closely related to the Bcl-2 family, a protein known to be involved in cell survival. AKT also ...

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• The Synergistic Cytotoxic Effect of Laser-Irradiated Gold Nanoparticles and Sorafenib Against the Growth of a Human Hepatocellular Carcinoma Cell Line 

  Ebrahim, Haidy M؛ El-Rouby, Mahmoud N؛ Morsy, Mona E؛ Said, Mahmoud M؛ Ezz, Magda K (West Asia Organization for Cancer Prevention (WAOCP), 2019-11-01)

  Gold nanoparticles are the most promising candidate in cancer treatment due to their physiochemical properties and increased use in photothermal therapy (PTT). In the present study, spherical gold nanoparticles (AuNPs) ...

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