Volume 12, Issue 10
مرور بر اساس
ارسال های اخیر
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Weekly TP Regimen as a Postoperative Adjuvant Chemotherapy for Completely Resected Breast Cancer in China: Final Result of a Phase II Trial
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)Objectives: To investigate the safety and long-term survival with weekly paclitaxel combined with cisplatin (wTP) as a postoperative adjuvant chemotherapy regimen for breast cancer. Methods: Patients ...
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Biliary Brush Cytology in the Assessment of Biliary Strictures at a Tertiary Center in Iran
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)Background: Confirmation of cholangiocarcinoma and other malignant bile duct stenosis is challenging. The aim of the current study was to assess the accuracy of brush cytology for diagnosis of malignant biliary ...
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Insufficient Screening Knowledge in Chinese Interns: A Survey in Ten Leading Medical Schools
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)This study aimed to investigate Chinese medical interns’ cancer knowledge and associated factors, focusing on cancer screening. Methods: A questionnaire survey was conducted in ten leading Chinese medical schools ...
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Never Smokers with Lung Cancer: Analysis of Genetic Variants
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)It is well-known that tobacco smoke is a definite causative agent important for human health. Epidemiological research has proven that smoking is a cause of various serious and fatal diseases. However, never-smokers comprise ...
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Genetic Changes in the PTEN Gene and their Association with Breast Cancer in Pakistan
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)The PTEN gene, a candidate tumor suppressor, is one of the more commonly inactivated and extensively studied genes in cancer. However, few data are available about the role of germ line mutations of this gene in sporadic ...
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Lack of Germ Line Changes in KISS1 and KAI1 Genes in Sporadic Head and Neck Cancer Patients of Pakistani Origin
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)Background: Head and neck cancer is included among the top five most commonly prevailing cancers worldwide. Abnormalities of either genetic or epigenetic factors are found responsible for the development and progression ...
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OGG1 Gene Sequence Variation in Head and Neck Cancer Patients in Pakistan
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)In Pakistani culture tobacco use is very high and a well known risk factor for developing head and neck cancer (HNC), tobacco smoke containing high quantities of chemical carcinogens such as aromatic amines and reactive ...
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Lansoprazole Induces Collagenous Colitis in the Colon of Mongolian Gerbils
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)Collagenous colitis (CC) is an illness characterized by chronic diarrhea with possible effects on neoplastic development, but there have been no reports in animals. We therefore tried to establish CC development in a ...
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Expressional Alterations and Transcript Isoforms of Metastasis Suppressor Genes (KAI1 & KiSS1) in Breast Cancer Patients
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)Background: Metastasis suppressor genes are involved in the inhibition of a cancer cell’s ability to metastasize. Down expression of such genes may contribute to pathogenesis of breast cancer. The aim of current ...
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Mortality of Oral Cavity Cancer in Iran
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)Background: Oral cavity cancer is the eighth most frequent cancer among men in the world. Its incidence varies widely geographically and two-thirds of the incident cases are diagnosed in developing countries. The ...
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Loss of Heterozygosity at 6p21 and HLA Class I Expression in Esophageal Squamous Cell Carcinomas in China
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)Background and objective: The loss or downregulation of human leukocyte antigen ( HLA-Ⅰ) has been proposed to contribute to immune evasion by cancer cells. Since the human leukocyte antigen (HLA-Ⅰ) complex is located at ...
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The Impact of Mammographic Breast Cancer Screening in Singapore: A Comparison Between Screen-detected and Symptomatic Women
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)Background: Breast cancer is the leading cause of cancer death amongst Singapore women. There are few studies evaluating the impact of mammographic screening among Asian women. This study aimed to examine differences ...
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Promoter Methylation and Genetic Polymorphism of Glutathione S-Transferase P1 Gene (GSTP1) in Thai Breast-cancer Patients
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)The GSTP1 gene encodes for a detoxification enzyme involved in protecting cells from carcinogens. In breast cancer, GSTP1 polymorphisms may produce lower effective enzyme detoxification properties and GSTP1 promoter ...
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Association and Correlation of Different Chemotherapeutic Regimens and Doses With Onset and Severity of Anemia Among Solid Cancer Patients
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)Introduction: Anemia is considered as one of the most frequent hematological demonstration of malignant diseases, which lead to momentous impairment in every tissues and organs of cancer patients and put them ...
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Clinicopathological Features and Survival of Testicular Tumours in a Southeast Asian University Hospital: A Ten-year Review
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)Introduction: Testicular cancer mainly affects young men worldwide. There is lack of published data on patients with this malignant condition from the Southeast Asian region. The aim of this study was therefore ...
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Antitumor Activity of NF-kB Decoy Oligodeoxynucleotides in a Prostate Cancer Cell Line
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)Background: Nuclear factor-kappaB (NF-kB), a transcription factor, is abundantly expressed in prostate cancer and regulates many tumor-related genes. Given the important roles of these genes in tumor control, the ...
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Interaction Between CYP19A1 Polymorphisms and Body Mass Index in the Risk of Endometrial Cancer in Postmenopausal Japanese Women
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)Extra-ovarian sex hormone production plays an important role in endometrial cancer in postmenopausal women. Aromatase, which is encoded by CYP19A1, is a key enzyme in estrogen biosynthesis after menopause. To examine the ...
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Detection and Genotyping of High-Risk HPV and Evaluation of Anti-Oxidant Status in Cervical Carcinoma Patients in Tamil Nadu State, India - a Case Control Study
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)Cervical cancer is the second common type of cancer among women worldwide, with the human papillomavirus (HPV) recognized as the major causative agent. The HPV 16/18 prevalance in cervical cancer patients from the Trichy ...
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Endostar Combined with Chemotherapy Versus Chemotherapy Alone for Advanced NSCLCs: A Meta-Analysis
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)To evaluate the clinical efficacy and safety of rh-endostatin (Endostar) combined with chemotherapy in the treatment of patients with non-small cell lung cancer (NSCLC), we selected data from the Cochrane Library, EMBASE, ...
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Protective Effects of Silymarin against Doxorubicin-induced Texicit
(West Asia Organization for Cancer Prevention (WAOCP), 2011-10-01)Objectives: The aim of the present study was to investigate the effect of silymarin on doxorubicin-induced toxicity to the rat kidney, heart, and liver. Materials and methods: A single dose of 10 mg/kg doxorubicin ...
