• Neoadjuvant Chemotherapy in Triple Negative Breast Cancer: Correlation between Androgen Receptor Expression and Pathological Response 

  Mohammed, Amrallah A؛ Elsayed, Fifi Mostafa؛ Algazar, Mohammed؛ Rashed, Hayam E؛ Anter, Abeer Hussien (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Background: There is growing evidence that the response to chemotherapy may be affected by Androgen Receptor (AR) expression suggesting that triple-negative breast cancers (TNBC) AR+ and quadruple negative breast cancer ...

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• Serum microRNA let-7a-1/let-7d/let-7f and miRNA 143/145 Gene Expression Profiles as Potential Biomarkers in HCV Induced Hepatocellular Carcinoma 

  Aly, Doaa Mamdouh؛ Gohar, Nadida Abdul- Hameed؛ Abd El-Hady, Afaf Ahmed؛ Khairy, Marwa؛ Abdullatif, Mona Mohsen (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Background: Egypt has the highest prevalence of hepatitis C virus (HCV) worldwide. Which make liver cirrhosis and hepatocellular carcinoma (HCC) major health concerns in Egypt. Circulating microRNAs (miRNAs) have been ...

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• Tissue Profile of CDK4 and STAT3 as Possible Innovative Therapeutic Targets in Urinary Bladder Cancer 

  Aboushousha, Tarek؛ Hammam, Olfat؛ Aref, Ahmed؛ Kamel, Amira؛ Badawy, Mohamed؛ Abdel Hamid, Amr (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Bladder cancer represents a global health problem. It ranks ninth in worldwide cancer incidence. In Egypt, carcinoma of the bladder is the most prevalent cancer, Bladder cancer has the highest recurrence rate of any ...

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• Potency of Pfeiffer’s Crystallization to Analyze Oral Leukoplakia and Squamous Cell Carcinoma 

  Makkar, Vanshika؛ Kamboj, Mala؛ Narwal, Anjali؛ Kapoor, Rajeev Kumar (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Objective: Oral cancer usually has an early precancerous stage before its actual malignant transformation. Although there are various approaches to diagnose early stages of cancer, yet there is one less explored, cost ...

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• Significance of 18F-FDG PET/CT in Characterization of Equivocal Lesions in High-Risk Testicular Carcinoma in Restaging Setting 

  Rasheed, Rashid؛ Al-Kandari, Fareeda؛ Ghanem, Mohammad؛ Marafi, Fahad؛ Usmani, Sharjeel (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Objectives: The present study aims to evaluate the role of Positron emission tomography (PET) -computed tomography (CT) with 18F-fluorodeoxyglucose (18F-FDG) in the restaging of high-risk testicular cancer. Methods: ...

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• Apoptosis Induced by Prednisolone Occurs without Altering the Promoter Methylation of BAX and BCL-2 Genes in Acute Lymphoblastic Leukemia Cells CCRF-CEM 

  Ganbarjeddi, Saiedeh؛ Azimi, Ako؛ Zadi Heydarabad, Milad؛ Hemmatzadeh, Maryam؛ Mohammadi, Shahin؛ Mousavi Ardehaie, Reza؛ Zamani, Majid؛ Baharaghdam, Sina؛ Esmaeili, Sajjad؛ Ghasemi, Amin (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Objective: one of the main mechanisms in which cancer cells are resistant to chemotherapy drugs and therapeutic strategies is resistance to apoptosis due to these anticancer factors. Regulating the expression of genes ...

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• Genetic Polymorphism of GSTP1, GSTM1 and GSTT1 Genes and Susceptibility to Chronic Myeloid Leukaemia 

  Idris, Hadeil ME؛ Elderdery, Abozer Y؛ Khalil, Hiba B؛ Mills, Jeremy (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Background: The development of cancer results from an imbalance between exposure to carcinogens and the capacity of various enzyme systems engaged in activation or in the detoxification of xenobiotics. The aim of the present ...

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• Dynamic Changes of Circulating Mir-155 Expression and the Potential Application as a Non-Invasive Biomarker in Breast Cancer 

  Anwar, Sumadi Lukman؛ Tanjung, Dewi Sahfitri؛ Fitria, Meutia Srikandi؛ Kartika, Aprilia Indra؛ Sari, Dwi Nur Indah؛ Rakhmina, Dinna؛ Wardana, Tirta؛ Astuti, Indwiani؛ Haryana, Sofia Mubarika؛ Aryandono, Teguh (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Background: Breast cancer incidence rates have been continuously increasing in majority nations with significant higher portion of cancer-related mortality in low- and middle-income countries. Developing new biomarker is ...

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• Sociodemographic and Reproductive Risk Factors for Breast Cancer: A Case-Control Study in the Setif Province, Northern Algeria 

  Hamdi-Cherif, Mokhtar؛ Serraino, Diego؛ Bouad, Souad؛ Dib, Adlane؛ Boudaoud, Khadidja؛ Atoui, Saida؛ Mergherm, Imene؛ Toffolutti, Federica؛ Bidoli, Ettore؛ Kara, Lamia؛ Ayat, Asma؛ Habia, Ghania؛ Makhloufi, Kenza؛ Bouchaibi, Imane؛ Kettaf, Sabah؛ Chenafi, Samiha؛ Dilmi, Douniazad؛ Bouhafs, Karima؛ Ablaoui, Bahadinne؛ Chaouche, Hadjira؛ Belbedj, Loubna؛ Nadjem, Asma؛ Lakab, Nawel؛ Virdone, Saverio؛ Panato, Chiara (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Background: The age-standardized rate of breast cancer (BC) increased nearly nine-fold in the last 30 years in Setif, Algeria. A case-control study was carried out to investigate the role of sociodemographic characteristics ...

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• Value of CCNA1 promoter methylation in triaging ASC-US cytology 

  Oranratanaphan, Shina؛ Kobwitaya, Kewalin؛ Termrungruanglert, Wichai؛ Triratanachat, Surang؛ Kitkumthorn, Nakarin؛ Mutirangura, Apiwat (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Background: Using HPV testing to triage ASC-US still has some problems of unnecessary colposcopy in many cases. A previous study reported that methylation of CCNA1, a tumor suppressor gene, can differentiate between low ...

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• Assessment of Serum CoQ10 Levels and other Antioxidant Markers in Breast Cancer 

  El-Attar, Eman؛ Kamel, Amel؛ Karmouty, Ahmed؛ Wehida, Nadine؛ Nassra, Rasha؛ El Nemr, Mohamed؛ Kandil, Noha Said (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Background: The balance of the oxidative state in the body is fundamental for the maintenance of homeostasis. It has been implicated in the onset and progression of several diseases including breast cancer. The way in which ...

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• Anti-Cancer Effects of Traditional Medicinal Herbs on Oral Squamous Cell Carcinoma 

  Dehghani Nazhvani, Ali؛ Sarafraz, Najmeh؛ Askari, Fatemeh؛ Heidari, Fahimeh؛ Razmkhah, Mahboobeh (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Backgrounds: Oral squamous cell carcinoma (OSCC) is among the most frequent oral cancers in individuals under 40. Documents have endorsed that a diet enriched with fruit and vegetables can banish the risk of developing ...

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• Analysis of Heterozygous BRCA1 5382ins Founder Mutation in a Cohort of Egyptian Breast Cancer Female Patients Using Pyrosequencing Technique 

  Gomaa Mogahed, Salwa H؛ Hamed, Yasser S؛ Ibrahim Moursy, Yassmin E؛ Mahomoud Saied, Marwa H (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Background: Up to half of the heritable mutations in breast cancer (BC) are attributed to BRCA1 and BRCA2 genes. The mutation prevalence is variable based on ethnicity and may be influenced by founder mutations. The aim ...

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• Inhibitory Effect of Polyclonal Antibodies Against HER3 Extracellular Subdomains on Breast Cancer Cell Lines 

  Mansouri-Fard, Samaneh؛ Ghaedi, Mojgan؛ Shokri, Mohammad-Reza؛ Bahadori, Tannaz؛ Khoshnoodi, Jalal؛ Golsaz-Shirazi, Forough؛ Jeddi-Tehrani, Mahmood؛ Amiri, Mohammad Mehdi؛ Shokri, Fazel (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Objective: Human epidermal growth factor receptor 3 (HER3) is a unique member of the tyrosine kinase receptors with an inactive kinase domain and is the preferable dimerization partner for HER2 which lead to potent tumorigenic ...

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• Progesterone Receptor Expression in the Benign Prostatic Hyperplasia and Prostate Cancer Tissues, Relation with Transcription, Growth Factors, Hormone Reception and Components of the AKT/mTOR Signaling Pathway 

  Spirina, Liudmila V؛ Kovaleva, Irina V؛ Usynin, Evgeny A؛ Goorbunov, Alexey K؛ Kondakova, Irina V (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Background: Progesterone receptor (PR) is a critical regulator in reproductive tissues that controls a variety of cellular processes. The objective of the study was to study the PR expression in patients with benign prostatic ...

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• Design, One Pot Synthesis and Molecular Docking Studies of Substituted-1H-Pyrido[2,1-b] Quinazolines as Apoptosis-Inducing Anticancer Agents 

  Bathula, Raju؛ Satla, Shobha Rani؛ Kyatham, Ramadevi؛ Gangarapu, Kiran (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Objective: The present study focused to build pyridine and quinazoline rings in a single molecule and designed a new fused Pyrido[2,1-b] quinazoline to have a better pharmacological activity. Material and Methods: A three ...

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• Cyclin D1 Gene Numerical Imbalances in Laryngeal Squamous Cell Carcinoma: A Tissue Microarray Grid Based Analysis 

  Kyrodimos, Efthymios؛ Papanikolaou, Vasileios؛ Tsiambas, Evangelos؛ Kikidis, Dimitrios؛ Peschos, Dimitrios؛ Ragos, Vasileios؛ Mastronikolis, Nicholas؛ Riziotis, Christos؛ Chrysovergis, Aristeidis (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Background: Deregulation of critical proteins involved in cell cycle stability, such as cyclins, is a frequent genetic event in the development and progression of solid malignancies. Concerning laryngeal squamous cell ...

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• MIR-107, MIR-223-3P and MIR-21-5P Reveals Potential Biomarkers in Penile Cancer 

  Pinho, Jaqueline Diniz؛ Silva, Gyl Eanes Barros؛ Teixeira Júnior, Antonio Augusto Lima؛ Belfort, Marta Regina de Castro؛ Mendes, Juliana Melo؛ Cunha, Isabela Wernerck da؛ Quintana, Luciana Gonçalves؛ Calixto, José de Ribamar Rodrigues؛ Nogueira, Leudivan Ribeiro؛ Coelho, Ronald Wagner Pereira؛ Khayat, André Salim (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Background: Inguinal lymph node involvement is the main prognostic factor in patients with penile cancer. However, there is a lack of marker/s for lymph node metastasis. microRNAs have been investigated as potential markers ...

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• Impact of New Standardized Population for Estimating Cancer Incidence in Indian Context- an Analysis from National Cancer Registry Programme (NCRP) 

  K, SathishKumar؛ K, Vaitheeswaran؛ S, Stephen؛ N, Sathya؛ Mathur, Prashant (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Objective: Standardization adjusts for variations in population age-distribution and provides a summary measure for the comparison of populations and comparisons of time-trends in population. Globally, several standard ...

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• Grading Gliomas Capability: Comparison between Visual Assessment and Apparent Diffusion Coefficient (ADC) Value Measurement on Diffusion-Weighted Imaging (DWI) 

  Phuttharak, Warinthorn؛ Thammaroj, Jureerat؛ Wara-Asawapati, Sakda؛ Panpeng, Kobporn (West Asia Organization for Cancer Prevention (WAOCP), 2020-02-01)

  Background: To compare diagnostic accuracy between DWI visual scale assessment and ADC value measurement of solid portion of the tumor in grading gliomas. Methods: This retrospective study included 38 patients who had ...

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