Volume 2, Issue 4

 

ارسال های اخیر

  • First Case of X-linked Recessive Anhidrotic Ectodermal Dysplasia with Immunodeficiency from Iran with Unusual Aspergillus infection 

    Momen, Tooba؛ Alborzi, Abdolvahab؛ Eslamian, Mohammad Hossein؛ Casanova, Jean-Laurent؛ picard, Capucine (Research Center For Immunodeficiencies, 2019-12-01)
    NEMO (NF-κB essential modulator) is a regulatory factor involved in signaling pathways of innate and adaptive immune system. Hypomorphic mutation of IKBKG gene on X chromosome leads to X-linked recessive anhidrotic ectodermal ...

  • NFKB2 mutation in a patient with lymphopenia and extreme cold sensitivity (a case report) 

    rezaei, arezou؛ shirmast, paniz؛ Eslamian, Mohammad Hossein (Research Center For Immunodeficiencies, 2019-12-01)
    NF-κB pathway is a complex protein playing an important role in regulating lymphocyte development, immune responses, inflammation, cell proliferation, and cell death. The NF-kB signaling pathway has been described to be ...

  • Gastrointestinal Manifestations in Patients with Common Variable Immunodeficiency 

    Mohammad Rida Al-Hussieni, Kawthar Jasim؛ Rasouli, Seyed Erfan؛ Azizi, Gholamreza؛ Mosavian, Mehdi؛ Matani, Rahman؛ Porrostami, Kumars؛ Qorbani, Mostafa؛ Tavakol, Marzieh (Research Center For Immunodeficiencies, 2019-12-01)
    Background: Common variable immunodeficiency (CVID) is one of the most prevalent symptomatic primary immunodeficiencies (PIDs), which manifest a wide clinical variability such as gastrointestinal (GI) disorder.Patients ...

  • Autoimmunity in Patients with Hyper IgM Syndrome 

    Delavari, Samaneh؛ Moeini Shad, Tannaz؛ Pashangzadeh, Salar (Research Center For Immunodeficiencies, 2019-12-01)
    Introduction: hyper-IgM (HIGM) syndrome is characterized by normal to increased serum IgM and very low or undetectable IgG, IgA, and IgE. HIGM (also known as class-switch recombination (CSR) defects) patients manifest ...

  • Why should TREC and KREC quantification assay be concerned to screen of newborns in developing countries? 

    Ghasemi, Amir (Research Center For Immunodeficiencies, 2019-12-01)
    Primary immunodeficiencies contain a group of several different diseases. Giving the fact that their clinical outcome ranges from mild to potentially life-threatening, detection of patients with these diseases in the ...

  • Precision Medicine as Treatment for Primary Immunodeficiency and Immune Dysregulation 

    Hoyos-Bachiloglu, Rodrigo؛ Platt, Craig (Research Center For Immunodeficiencies, 2019-12-01)
    “Precision medicine" is the use of therapy that targets the molecular basis of a patient's disease process. This approach is increasingly well-established in treatment of monogenic disorders of immunity, including primary ...