Volume 6, Issue 3
مرور بر اساس
ارسال های اخیر
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Antibacterial and anti-biofilm effects of microwave-assisted biologically synthesized zinc nanoparticles
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): The present study aimed to investigate the antibacterial and anti-biofilm potential of the non-oxidized form of zinc nanoparticles (Zn NPs) prepared by a ‘green approach' using the Lavandula vera extract with ...
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Effects of combined 5-Fluorouracil and ZnO NPs on human breast cancer MCF-7 Cells: P53 gene expression, Bcl-2 signaling pathway, and invasion activity
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): The significant contribution of nanoparticles to cancer treatment has attracted therapeutic attention. The present study aimed to evaluate the synergistic effects of 5-fluorouracil (5-FU) and zinc oxide ...
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An artificial blood vessel fabricated by 3D printing for pharmaceutical application
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): Cardiovascular diseases (CVDs) are the leading cause of mortality in the elderly. A common medical procedure for the treatment of CVDs is the replacement of the blocked or narrowed arteries, which is currently ...
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ShRNA-mediated knock-down of CD200 using the self-assembled nanoparticle-forming derivative of polyethylenimine
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): ShRNA-mediated silencing strategy is considered to be a potent therapeutic approach. The present study aimed to assess the ability of the previously prepared polyethylenimine (PEI) derivative for the shRNA ...
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Application of near-infrared light intensity to determine normal and cancerous breast vessel contrast by gold nanoparticles
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): A novel technique for the early diagnosis of breast cancer involves the use of nanoparticles (NPs). The present study aimed to use gold NPs to assess the variations in light source transfer intensity.
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Potential positive MRI contrast agent based on PVP-grafted superparamagnetic iron oxide nanoparticles with various repetition times
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): The present study aimed to evaluate the capability of synthesized and modified superparamagnetic iron oxide nanoparticles (SPIONs) as the positive contrast agent in magnetic resonance imaging (MRI) by ...
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The effects of indirect exposure of nanosilver on caspase-8 and caspase-9 levels in liver and brain of suckling rats
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): The adverse health effects of nanosilver (AgNp) on adult animal models have been well documented. However, data is scarce regarding the toxic effects of AgNp on sensitive developmental stages. The present ...
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Investigation of osteoblast-like cells cultured on nano-hydroxyapatite/chitosan based composite scaffold in the treatment of bone defects and limited mobility
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): Design and construction of biocompatible and biodegradable scaffolds are among the main goals of tissue engineering. Recently, use of nano-hydroxyapatite as a bioactive bioceramic agent with high similarity ...
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Assessment of pulmonary mucociliary transport using magnetic nanoparticles: influence of their surface potential
(Mashhad University of Medical Sciences, 2019-07-01)Objective(s): Inhaled aerocontaminants are removed from the lungs by pulmonary mucociliary transport (MCT) as an important defense mechanism. This study was undertaken to investigate the influence of the surface potential ...
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Gold nanoparticles as cancer theranostic agents
(Mashhad University of Medical Sciences, 2019-07-01)The application of nanotechnology in medicine involves using nanomaterials to develop novel therapeutic and diagnostic modalities. Given the unique physiochemical and optical properties of gold nanoparticle (GNP) such as ...
