| dc.description.abstract | Background: Brucellosis is one of the endemic and a Zoonotic disease of the Iran.
Science the rapid diagnosis and quick treatment are very important, selection of a
sensitive and specific test solving this problem is of a great importance. The main aim
of this study is comparison of routine serologic test with standard Elisa test.
Materials and methods: In this survey, 176 suspected patients with conformed
clinical signs, were selected and them routine diagnostic test like Wright (rapid),
Standard tube agglutination (STA), Coombs Wright test and selective and quantitative
Elisa test was performed for all sample referred to diagnostic laboratory.
Findings: out of 176 sample, 92 (52.27%) were male and 84 (47.73%) female. On
performing Wright (rapid), standard tube agglutination (STA), Coombs Wright and
Elisa, 45 (25.57%), 49 (27.84%), 58 (32.95%) and 72 (40.91%) sample were positive
respectively. The range of age distribution was 15-65 years. The geographical
distribution of population is 72.4% rural and 27.6% of urban category. The sensitivity
of above mentioned test as compare to Elisa was 62.5, 68.0 and 80.0 percent
respectively with 100% of specificity for all.
Conclusions: The Elisa posses the highest diagnostic value as compare to other
routinely performed tests. After Elisa other test namely Coombs Wright, standard tube
agglutination and Wright (rapid) respectively. Have the highest diagnostic value with
consideration to above findings, it is obvious that due to ability to find quantitative
value, determination of antibody classis and stage of disease, Elisa is the best method
of choice in diagnosis of brucellosis. | en_US |
