نمایش مختصر رکورد

dc.contributor.authorKhajali, Fariborzen_US
dc.contributor.authorFaraji, Mehraben_US
dc.date.accessioned1402-02-07T22:45:33Zfa_IR
dc.date.accessioned2023-04-27T22:45:34Z
dc.date.available1402-02-07T22:45:33Zfa_IR
dc.date.available2023-04-27T22:45:34Z
dc.date.issued2022-09-01en_US
dc.date.issued1401-06-10fa_IR
dc.date.submitted2022-02-28en_US
dc.date.submitted1400-12-09fa_IR
dc.identifier.citationKhajali, Fariborz, Faraji, Mehrab. (2022). Application of Trimethylglycine Supplement in Broiler Chicken’s Diets with a High Dose of Dietary Guanidinoacetic Acid: Influence on Growth Performance and Physiological Variables. Poultry Science Journal, 10(2), 197-202. doi: 10.22069/psj.2022.19998.1784en_US
dc.identifier.issn2345-6604
dc.identifier.issn2345-6566
dc.identifier.urihttps://dx.doi.org/10.22069/psj.2022.19998.1784
dc.identifier.urihttps://psj.gau.ac.ir/article_6144.html
dc.identifier.urihttps://iranjournals.nlai.ir/handle/123456789/964007
dc.description.abstractThe present experiment studied the effect of a high dose of guanidinoacetic acid (GAA; 2.25 g/kg), with or without trimethylglycine (TMG) on growth performance and physiological variables of broiler chickens. A total of 300 day-old males Cobb 500 were randomly assigned to three dietary treatments with 5 replicates of 10 birds in each. Treatments were including a basal diet (control treatment), the basal diet supplemented with 2.25 g/kg GAA, and the GAA diet with 1 g/kg TMG. All birds received feed and water ad libitum during a 40-days rearing period. Results indicated that weight gain during days 31-40 of the rearing period was impaired by feeding the GAA diet. Feed conversion ratio was impaired in all feeding stages when the high dose of GAA was included in the diet. However, the inclusion of TMG in the GAA diet restored these responses to a comparable level to the control group. The GAA diet caused a significant increase in malondialdehyde concentration in serum compared to the control treatment. Moreover, the use of GAA decreased the heterophil to lymphocyte ratio than other treatments. A high dose of GAA caused higher serum levels of creatine and homocysteine; however, TMG supplementation re-established those responses. In addition, TMG supplement significantly up-regulated hepatic adenosyl homocysteinase and methionine adenosyltransferase II beta genes. In conclusion, feeding a high dose of GAA could impact broiler growth performance, but this effect could be ameliorated by dietary inclusion of TMG supplement, suggesting the negative effects of high doses of GAA were linked to the methyl donor deficiency. The practical implication is to include TMG in diets when a high dose of GAA is going to feed.en_US
dc.format.extent448
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoen_US
dc.publisherGorgan University Of Agricultural Sciences & Natural Resourcesen_US
dc.relation.ispartofPoultry Science Journalen_US
dc.relation.isversionofhttps://dx.doi.org/10.22069/psj.2022.19998.1784
dc.subjectHomocysteineen_US
dc.subjectMethyl donoren_US
dc.subjectBroiler chickenen_US
dc.subjectGuanidinoacetic aciden_US
dc.titleApplication of Trimethylglycine Supplement in Broiler Chicken’s Diets with a High Dose of Dietary Guanidinoacetic Acid: Influence on Growth Performance and Physiological Variablesen_US
dc.typeTexten_US
dc.typeOriginal Paperen_US
dc.contributor.departmentDepartment of Animal Science, Shahrekord University, Shahrekord, 88186-34141, Iranen_US
dc.contributor.departmentDepartment of Animal Science, Shahrekord University, Shahrekord, 88186-34141, Iranen_US
dc.citation.volume10
dc.citation.issue2
dc.citation.spage197
dc.citation.epage202


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