نمایش مختصر رکورد

dc.contributor.authorNish, Sainien_US
dc.contributor.authorMathew, Georgeen_US
dc.contributor.authorLincy, Josephen_US
dc.date.accessioned1399-07-08T20:01:24Zfa_IR
dc.date.accessioned2020-09-29T20:01:24Z
dc.date.available1399-07-08T20:01:24Zfa_IR
dc.date.available2020-09-29T20:01:24Z
dc.date.issued2012-07-01en_US
dc.date.issued1391-04-11fa_IR
dc.date.submitted2012-03-02en_US
dc.date.submitted1390-12-12fa_IR
dc.identifier.citationNish, Saini, Mathew, George, Lincy, Joseph. (2012). Matrix Tablets: An Effective Way for Oral Controlled Release Drug Delivery. Iranian Journal of Pharmaceutical Sciences, 8(3), 165-170.en_US
dc.identifier.issn1735-2444
dc.identifier.urihttp://www.ijps.ir/article_2269.html
dc.identifier.urihttps://iranjournals.nlai.ir/handle/123456789/79490
dc.description.abstractThe purpose of this review article is to characterize all of the parameters regarding the types, polymers used, and release kinetics of matrix tablets. Matrix system was the earliest oral extended release platform for medicinal use. Matrix tablets are most commonly used methods to modulate the release profile of drugs. They are much desirable and preferred for such therapy because they offer better patient compliance, maintain uniform drug levels, reduce dose and side effects, and increase safety margin for high potency drugs. Hydrophilic polymer matrix systems are widely used for designing oral controlled drug delivery dosage forms because of their flexibility to provide a desirable drug release profile, cost effectiveness, and broad regulatory acceptance. However, the use of hydrophilic matrix alone for extending drug release for highly water soluble drugs is restricted due to rapid diffusion of the dissolved drug through the hydrophilic gel network. For such drugs it becomes essential to include hydrophobic polymers in the matrix system. This leads to the conclusion that matrix tablets seem to be most promising when developing an oral controlled release formulation.en_US
dc.format.extent192
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoen_US
dc.publisherIranian Association of Pharmaceutical Scientistsen_US
dc.relation.ispartofIranian Journal of Pharmaceutical Sciencesen_US
dc.subjectControlled releaseen_US
dc.subjectHydrophilic matrixen_US
dc.subjectHydrophobic matrixen_US
dc.subjectMatrix tabletsen_US
dc.subjectPolymersen_US
dc.titleMatrix Tablets: An Effective Way for Oral Controlled Release Drug Deliveryen_US
dc.typeTexten_US
dc.contributor.departmentSchool of Pharmaceutical Sciences, Shoolini University Solan (H.P), Indiaen_US
dc.contributor.departmentSchool of Pharmaceutical Sciences, Shoolini University Solan (H.P), Indiaen_US
dc.contributor.departmentSchool of Pharmaceutical Sciences, Shoolini University Solan (H.P), Indiaen_US
dc.citation.volume8
dc.citation.issue3
dc.citation.spage165
dc.citation.epage170


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