Iranian Journal of Pharmaceutical Sciences
مرور بر اساس
مجموعههای این پایگاه
ارسال های اخیر
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Possible Rapid Therapeutics for SARS Coronavirus 2 RNA-dependent RNA polymerase: A Systematic Review
(Iranian Association of Pharmaceutical Scientists, 2022-07-01)Abstract Background: Research confirms that viral polymerases play a key role in viral genome replication and transcription. HenceAccordingly, they are essential for the multiplication and survival of viral particles. ...
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Evaluation of the effect of Medicago sativa on Lipid Profile and Iron Indices in Healthy Volunteers
(Iranian Association of Pharmaceutical Scientists, 2022-07-01)Medicago sativa (alfalfa) has a long history of traditional use. Several studies indicate that the ingestion of M. sativa reduces cholesterol absorption and atherosclerotic plaque formation in animals and has been reported ...
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Heavy Metals in Over-the-Counter Pediatric Drugs Locally Produced in Uganda: A Stare at Manganese, Lead, and Cadmium
(Iranian Association of Pharmaceutical Scientists, 2022-07-01)This study evaluated the amounts of lead (Pb), cadmium (Cd), and manganese (Mn) in pediatric over-the-counter medications made in Uganda. Twelve distinct brands from four categories of pediatric medications (antihistamine, ...
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Population Pharmacokinetic Study of Gabapentin in Iranian Healthy Volunteers
(Iranian Association of Pharmaceutical Scientists, 2022-07-01)The objective of the study was to evaluate the pharmacokinetics of a single oral dose of 300 mg gabapentin capsule in an Iranian healthy population. The study was a standard two-way, crossover, randomized, and single-dose ...
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In vitro antimalarial activity of the biosurfactant produced by Serratia marcescens MBC1
(Iranian Association of Pharmaceutical Scientists, 2022-07-01)Serratia is a bacterium with a distinctive red-pigment prodigiosin, known as a plasmodium growth inhibitor. This species is also known for its reliability as a producer of biosurfactants. Furthermore, the ability of these ...
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Analysis of Inequality in the Distribution of Various Types of Pharmacies Using the Gini Coefficient and Lorenz Curve
(Iranian Association of Pharmaceutical Scientists, 2022-07-01)Inequitable distribution of health resources leads to high costs and sustainable poverty for households. Therefore, it is necessary to study distribution in health. The most common indicator for measuring inequality is the ...
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Evaluation of immune responses induced by hydroalcoholic extract of Allium ampeloprasum. L subsp iranicum in mice
(Iranian Association of Pharmaceutical Scientists, 2022-07-01)The extract of some plants can play a role in modulating the function of the human immune system. A number of studies show that Allium species can stimulate the immune system through different cellular mechanisms. In this ...
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Designing a new Vaccine Based on Multiple Epitopes Against Monkeypox Virus with the help of new Methods Based on Immunoinformatics Software
(Iranian Association of Pharmaceutical Scientists, 2022-04-01)Monkeypox virus is a zoonotic virus belonging to the family of Poxviridae and the genus Orthopoxvirus, which is the cause of a viral disease between humans and animals, the characteristics of which are comparable to other ...
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The Effect of Synthesized Triazole and Ciprofloxacin Conjugated Peptide Compounds on Biological systems
(Iranian Association of Pharmaceutical Scientists, 2022-04-01)Breast cancer is the most common cancer among women and only second in terms of cancer-related death in women. Finding new approaches to treat such cancers is critically important anti-cancer peptides (ACPs) offer the ...
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Protective Effects of Memantine, an NMDA Receptor Antagonist, Against Cerebral Ischemia/Reperfusion Induced Injuries in Rats with Transient Congenital Hypothyroidism
(Iranian Association of Pharmaceutical Scientists, 2022-04-01)Stroke is one of the major causes of mortality worldwide. Memantine, an NMDA receptor antagonist, has protective effects on neuronal cells and is important candidate as a neuroprotective agent in cerebral ischemia. On the ...
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The Selective Cytotoxicity of The Hydroalcoholic Extract of Santalum Album Linn Wood on A375 and SK-MEL-3 Human Malignant Melanoma Cells
(Iranian Association of Pharmaceutical Scientists, 2022-04-01)Melanoma is the cause of most skin cancer all around the world because of its high proliferation rate, metastatic nature, and limited effective therapies. According to the rapid increment in its incidence compared to other ...
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In Vitro Evaluation the Anti-Melanogenic Effects of Various Extracts of Oat Seeds
(Iranian Association of Pharmaceutical Scientists, 2022-04-01)This study was designed to examine the effects of aqueous and hydroalcoholic extracts of oats (Avena sativa), rich in beta-glucan, and with established anti-pigmentation effects, on the melanin biosynthesis rate in melanocyte ...
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Effect of intraductal drug delivery of orexin receptor antagonists into rat mammary gland on milk triacylglycerol level: Possible molecular interaction with Gpat1 and Gpat4 genes
(Iranian Association of Pharmaceutical Scientists, 2022-04-01)Although previous studies have demonstrated the importance of the orexin system in regulating enzymes involved in lipogenesis, its exact mechanism and the extent of this effect on different enzymes have remained unexplored. ...
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Antioxidant and Cytotoxic Effects of Aqueous Extract of Iranian Green Tea (Camellia sinensis L.)
(Iranian Association of Pharmaceutical Scientists, 2022-01-01)Green tea, a common beverage, has several pharmacological effects. In this study, the amounts of phenoliccompounds and epigallocatechin (EGC) were determined in an aqueous extract of green tea planted in Lahijan (acity in ...
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Biological Evaluation of New oxadiazole-based Synthetic α-glycosidase Inhibitors for Hyperglycemia Management
(Iranian Association of Pharmaceutical Scientists, 2022-01-01)The present study was conducted to investigate the hypoglycemic activity of 3,4,5-triphenyl-oxadiazole derivativesand its effects on liver, lung, and kidney function in streptozotocin (STZ)-induced diabetic rats. For this ...
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Design, Synthesis and Docking studies of New Quinazolinone Derivatives as Anti-HIV-1 Agents
(Iranian Association of Pharmaceutical Scientists, 2022-01-01)The Human Immunodeficiency Virus (HIV) infection is a global health challenge that creates an urgent need todevelop new therapeutic agents. In this work, a new group of quinazolinone derivatives were designed andsynthesized ...
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UV Induced Biosynthesis of Cyano-sunscreen “Scytonemin” by Leptolyngbya mycodia and its Effectual Antioxidant Activity
(Iranian Association of Pharmaceutical Scientists, 2022-01-01)The indole-alkaloid scytonemin, an ecologically and pharmaceutically important secondary metabolite, isexclusively biosynthesized by some cyanobacteria. Due to its photoprotective function and valuable antioxidantcapacity, ...
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Therapeutic Potential of Astaxanthin Against Cadmium-Induced Hepatic Failure: An Experimental Study
(Iranian Association of Pharmaceutical Scientists, 2022-01-01)Cadmium is a toxic metal that can lead to liver failure in humans and animals. Astaxanthin (ASX) is one of the wellknown xanthophyll carotenoids in food that has remarkable antioxidant properties. Hence, this study ...
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In-silico Strategies of Some Selected Phytoconstituents from Rhus succedanea as SARS CoV-2 Main Protease and Spike protein (COVID-19) Inhibitors
(Iranian Association of Pharmaceutical Scientists, 2021-10-01)Rhus succedanea (Anacardiaceae) was used to treat multiple human afflictions. Literary works demonstrate that it has many biological activities. Today's research aims to recognise Rhus succedanea phyto-derived anti-viral ...
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The Pattern of Albumin Consumption in Teaching University Hospitals in Northeastern Iran
(Iranian Association of Pharmaceutical Scientists, 2021-10-01)Insufficient information on accurate indications of albumin administrations and the lack of acceptable protocols emphasize the importance of performing further studies on the albumin consumption. So, the current study aimed ...
