نمایش مختصر رکورد

dc.contributor.authorAlireza Nakhaeeen_US
dc.contributor.authorMohammad Hashemien_US
dc.contributor.authorAlireza Rezaeifaren_US
dc.contributor.authorMahmoud Ali Kaykhaeien_US
dc.date.accessioned1399-12-09T06:17:37Zfa_IR
dc.date.accessioned2021-02-27T06:17:47Z
dc.date.available1399-12-09T06:17:37Zfa_IR
dc.date.available2021-02-27T06:17:47Z
dc.date.issued2015-05-24en_US
dc.date.issued1394-03-03fa_IR
dc.date.submitted2013-10-20en_US
dc.date.submitted1392-07-28fa_IR
dc.identifier.citationAlireza Nakhaee, Mohammad Hashemi, Alireza Rezaeifar, Mahmoud Ali Kaykhaei. (2015). Evaluation of haptoglobin genotypes in patients with metabolic syndrome: A preliminary report. ARYA Atherosclerosis, 11(3), 167-172.en_US
dc.identifier.issn1735-3955
dc.identifier.issn2251-6638
dc.identifier.urihttp://arya.mui.ac.ir/index.php/arya/article/view/818
dc.identifier.urihttps://iranjournals.nlai.ir/handle/123456789/782596
dc.description.abstractBACKGROUND: Haptoglobin (Hp) polymorphisms have been suggested to be associated with many pathological conditions, including cardiovascular diseases, infectious diseases, and type 2 diabetes. For the first time, we aimed to investigate the possible association between Hp genotypes and metabolic syndrome (MES) in a sample of Iranian subjects. METHODS: In this study, 291 patients with MES according to National Cholesterol Education Program-Adult Treatment Panel III criteria, and 284 healthy individuals have been studied. We determined Hp genotype by polymerase chain reaction. RESULTS: The frequency of three genotype (Hp1-1, Hp2-1, and Hp2-2) in healthy individuals and patients were 7.74, 39.7, 52.46, and 7.9, 31.61, 60.48 percent, respectively. There was no significant difference between the groups regarding Hp genotypes. The Hp2 allele was the predominant allele in MES (76.29%) and normal subjects (72.54%). CONCLUSION: Hp polymorphisms are not risk factor for predisposition to MES in a sample of the Iranian population. Further studies with different ethnicities are required to validate our findings.en_US
dc.languageEnglish
dc.language.isoen_US
dc.publisherIsfahan, Isfahan University of Medical Sciencesen_US
dc.relation.ispartofARYA Atherosclerosisen_US
dc.subjectHaptoglobinen_US
dc.subjectPhenotypeen_US
dc.subjectMetabolic Syndromeen_US
dc.titleEvaluation of haptoglobin genotypes in patients with metabolic syndrome: A preliminary reporten_US
dc.typeTexten_US
dc.contributor.departmentAssociate Professor, Cellular and Molecular Research Center AND Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iranen_US
dc.contributor.departmentProfessor, Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iranen_US
dc.contributor.departmentLecturer, Department of Clinical Biochemistry, Zabol University of Medical Sciences, Zabol, Iranen_US
dc.contributor.departmentAssistant Professor, Department of Internal Medicine, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iranen_US
dc.citation.volume11
dc.citation.issue3
dc.citation.spage167
dc.citation.epage172


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