Colocalization of Vitiligo and Verrucous Epidermal Nevus: A Simulator of Depigmented Variant of Verrucous Epidermal Nevus

Abstract

Vitiligo, an autoimmune disorder, is known to co-localize with other immunological disorders like lichen planus and psoriasis. However, there are no reports regarding the co-localization of an autoimmune disorder (vitiligo) and a developmental disorder (verrucous epidermal nevus). We hereby present a 10-month-old infant who was visited for white patches on the right buttock and adjoining anterolateral thigh since 2 months of age. Lesions started as flat depigmented patches which gradually became raised. Examination revealed depigmented verrucous plaques along Blaschko's lines on the right buttock and adjoining thigh with depigmented macules and patches in the periphery. Histopathology revealed features of classical verrucous epidermal nevus in addition to focal interface dermatitis. Immunohistochemistry showed melanocytopenia. Hence, this was a rare case of verrucous epidermal nevus co-localized with a vitiliginous patch, clinically simulating a depigmented variant of verrucous epidermal nevus.