Pyoderma gangrenosum in a patient with antiphospholipid antibody negative systemic lupus erythematosus: A case report

Abstract

In any description of leg ulcers in systemic lupus erythematosus (SLE), pyoderma gangrenosum (PG) earns a mention at least for its being quite rare in such patients. The causative role of aPL (antiphospholipid antibody) in dermatological manifestations of SLE is undermined by the occurrence of PG in aPL negative SLE patients. To the best of our knowledge, there are only two reports of PG in aPL negative SLE patients; in one, PG preceded the diagnosis of SLE by several years while the other was associated with the reactivation of the disease in an already diagnosed SLE patient. In view of the rarity of this association, we hereby present another similar case to substantiate the documentation of the association of the entities.