نمایش مختصر رکورد

dc.contributor.authorPirnia, Bijanen_US
dc.contributor.authorMasoudi, Rahelehen_US
dc.contributor.authorPirnia, Kambizen_US
dc.contributor.authorJalali, Minaen_US
dc.contributor.authorEslami, Mohammad Rezaen_US
dc.contributor.authorMalekanmehr, Parastooen_US
dc.contributor.authorPirnia, Fariborzen_US
dc.contributor.authorAjori, Ladanen_US
dc.date.accessioned1399-10-19T15:35:14Zfa_IR
dc.date.accessioned2021-01-08T15:35:16Z
dc.date.available1399-10-19T15:35:14Zfa_IR
dc.date.available2021-01-08T15:35:16Z
dc.date.issued2020-10-01en_US
dc.date.issued1399-07-10fa_IR
dc.date.submitted2021-01-06en_US
dc.date.submitted1399-10-17fa_IR
dc.identifier.citationPirnia, Bijan, Masoudi, Raheleh, Pirnia, Kambiz, Jalali, Mina, Eslami, Mohammad Reza, Malekanmehr, Parastoo, Pirnia, Fariborz, Ajori, Ladan. (2020). Effect of Magnesium Sulfate Added to Tincture of Opium and Buprenorphine on Pain and Quality of Life in Women with Dysmenorrhea: A Prospective, Randomized, Double-blind, Placebo-controlled Trial. Addiction and Health, 12(4), 259-268. doi: org/10.22122/ahj.v12i4.285en_US
dc.identifier.issn2008-4633
dc.identifier.issn2008-8469
dc.identifier.urihttps://dx.doi.org/org/10.22122/ahj.v12i4.285
dc.identifier.urihttp://ahj.kmu.ac.ir/article_91539.html
dc.identifier.urihttps://iranjournals.nlai.ir/handle/123456789/709523
dc.description.abstractBackground: Adding magnesium sulfate (MgSO4) to opioid receptor agonists increases the opioid analgesiceffects via blocking this receptor. The current study aimed to evaluate the effectiveness of adding MgSO4 totincture of opium (TOP) and buprenorphine (BUP) on pain and quality of life (QOL).Methods: In prospective, randomized, double-blind, placebo-controlled clinical trial, one hundred andsixty-three women with secondary dysmenorrhea caused by endometriosis were selected using a respondentdriven sampling (RDS) and assigned into six groups using block randomization. Patients received 50 mg/kgMgSO4 in 100 ml saline by micro set in six monthly menstrual periods and completed the visual analoguescale (VAS) and QOL Questionnaire (QOLQ). Data were analyzed by repeated measures analysis of variance(ANOVA) and hierarchical regression.Findings: The primary outcomes showed that pain scores in magnesium (MAG) + opium tincture (OT)[F = 5.7(1,162), P = 0.004] and MAG+ BUP [F = 4.5(1,162), P = 0.006] groups showed a significant decreasecompared with control group. Also, QOL scores in MAG + OT [F = 4.8(1,162), P = 0.005] and MAG + BUP[F = 5.9(1,162), P = 0.003] showed a significant increase. However, there was no significant differencebetween the two groups (P = 0.140) and the changes did not persist until follow-up (P = 0.810). Secondaryoutcomes indicated that the low scores of the two components of QOL including physical and psychologicalcomponents were predictors of pain (P = 0.011, Beta > 3.09).Conclusion: Simultaneous use of MAG with opioids is associated with pain reduction and the improvement ofQOL. However, this hypothesis requires careful handling in a randomized controlled trialen_US
dc.format.extent1116
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoen_US
dc.publisherKerman University of Medical Sciencesen_US
dc.relation.ispartofAddiction and Healthen_US
dc.relation.isversionofhttps://dx.doi.org/org/10.22122/ahj.v12i4.285
dc.subjectDysmenorrheaen_US
dc.subjectEndometriosisen_US
dc.subjectPainen_US
dc.subjectmagnesium sulfateen_US
dc.subjectBuprenorphineen_US
dc.titleEffect of Magnesium Sulfate Added to Tincture of Opium and Buprenorphine on Pain and Quality of Life in Women with Dysmenorrhea: A Prospective, Randomized, Double-blind, Placebo-controlled Trialen_US
dc.typeTexten_US
dc.typeOriginal Articleen_US
dc.contributor.departmentDepartment of Psychology, School of Humanities, University of Science and Culture AND Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iranen_US
dc.contributor.departmentDepartment of Midwifery, School of Medicine, Qom Branch, Islamic Azad University, Qom, Iranen_US
dc.contributor.departmentBijan Center for Substance Abuse Treatment, Tehran, Iranen_US
dc.contributor.departmentDepartment of Psychology, Kish International Branch, Islamic Azad University, Kish, Iranen_US
dc.contributor.departmentDepartment of Health Psychology, North Tehran Branch, Islamic Azad University, Tehran, Iranen_US
dc.contributor.departmentDepartment of Psychology, School of Psychology, Tonekabon Branch, Islamic Azad University, Tonekabon, Iranen_US
dc.contributor.departmentDepartment of Food Science and Technology, School of Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iranen_US
dc.contributor.departmentPreventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iranen_US
dc.citation.volume12
dc.citation.issue4
dc.citation.spage259
dc.citation.epage268


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